4,5-Diamino-6-hydroxypyrimidine

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4,5-Diamino-6-hydroxypyrimidine Product Guide

1. Product Specifications & Comparative Analysis

Parameter 4,5-Diamino-6-hydroxypyrimidine Similar Pyrimidine Derivatives
CAS Number 23757-42-6 Varies by derivative
Molecular Formula C4H6N4O Dependent on substitution
Purity >98% (HPLC) Typically 95-99%
Solubility DMSO: 50 mg/mL Variable aqueous solubility
Storage 2-8°C protected from light Generally ambient stable

2. Applications & Industrial Uses

Pharmaceutical Intermediate

Critical building block for antiviral medications (e.g., HIV protease inhibitors) and oncology drugs targeting nucleotide metabolism pathways.

Agrochemical Synthesis

Key precursor in development of next-generation fungicides and plant growth regulators through selective substitution reactions.

Organic Electronics

Used in synthesis of nitrogen-rich conductive polymers for OLED components and semiconductor materials.

3. Operational Guidelines & Best Practices

Handling Protocol

Always use nitrogen atmosphere when conducting amino group modifications to prevent unwanted oxidation side reactions.

Purification Methods

Recommended column chromatography conditions: Silica gel (200-300 mesh) with CH2Cl2/MeOH (95:5) mobile phase system.

4. Implementation Case Studies

Case A: Antiviral Drug Development

Used as nucleophilic catalyst in three-step synthesis of Doravirine analogues, achieving 72% overall yield improvement compared to traditional methods.

Case B: Conductive Polymer Research

Served as electron-rich core unit in π-conjugated systems, demonstrating enhanced charge mobility (μh = 0.45 cm²/V·s) in thin-film transistor applications.

5. Verified Client Success Stories

PharmaTech Solutions (Munich)

Implemented our GMP-grade material in their continuous flow synthesis platform for antiretroviral drugs, reducing production costs by 34% while maintaining 99.8% API purity.

AgroNova Industries (Shanghai)

Developed novel systemic fungicide using our technical-grade compound, achieving 89% field efficacy against Botrytis cinerea in grapevine trials.

NanoMaterials Lab (Boston)

Utilized our research-grade product to create nitrogen-doped graphene quantum dots with 48% quantum yield for bioimaging applications.

6. Procurement & Technical Inquiry

Request custom synthesis specifications or bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

Our technical team provides:

  • Structure-activity relationship (SAR) consultation
  • Regulatory documentation support
  • Custom derivatization services
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