| Parameter | 4,5-Diamino-6-hydroxypyrimidine | Similar Pyrimidine Derivatives |
|---|---|---|
| CAS Number | 23757-42-6 | Varies by derivative |
| Molecular Formula | C4H6N4O | Dependent on substitution |
| Purity | >98% (HPLC) | Typically 95-99% |
| Solubility | DMSO: 50 mg/mL | Variable aqueous solubility |
| Storage | 2-8°C protected from light | Generally ambient stable |
Critical building block for antiviral medications (e.g., HIV protease inhibitors) and oncology drugs targeting nucleotide metabolism pathways.
Key precursor in development of next-generation fungicides and plant growth regulators through selective substitution reactions.
Used in synthesis of nitrogen-rich conductive polymers for OLED components and semiconductor materials.
Always use nitrogen atmosphere when conducting amino group modifications to prevent unwanted oxidation side reactions.
Recommended column chromatography conditions: Silica gel (200-300 mesh) with CH2Cl2/MeOH (95:5) mobile phase system.
Used as nucleophilic catalyst in three-step synthesis of Doravirine analogues, achieving 72% overall yield improvement compared to traditional methods.
Served as electron-rich core unit in π-conjugated systems, demonstrating enhanced charge mobility (μh = 0.45 cm²/V·s) in thin-film transistor applications.
Implemented our GMP-grade material in their continuous flow synthesis platform for antiretroviral drugs, reducing production costs by 34% while maintaining 99.8% API purity.
Developed novel systemic fungicide using our technical-grade compound, achieving 89% field efficacy against Botrytis cinerea in grapevine trials.
Utilized our research-grade product to create nitrogen-doped graphene quantum dots with 48% quantum yield for bioimaging applications.
Request custom synthesis specifications or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Our technical team provides:
This is William, CEO of fousi chemical Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
