![1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one](https://chem-iso.com/wp-content/uploads/2024/12/6969-71-7.gif)
Table of Contents
- Basic Information & Specifications
- Key Applications & Industrial Uses
- Research Case Studies
- Client Success Stories
- Request Quotation
Basic Information & Specifications
Chemical Profile
| Parameter | Value |
|---|---|
| IUPAC Name | 8-Hydroxyquinoline-2-carboxaldehyde |
| CAS Number | 14510-06-6 |
| Molecular Formula | C10H7NO2 |
| Molecular Weight | 173.16 g/mol |
| Appearance | Yellow crystalline powder |
| Melting Point | 97–100°C |
| Boiling Point | 392.2°C at 760 mmHg |
| Flash Point | 191°C |
Safety Data
| Hazard Code | Risk Statements | Safety Precautions |
|---|---|---|
| Xi | H315/H319/H335 | P261, P305+P351+P338 |
Key Applications & Industrial Uses
Coordination Chemistry
Acts as a versatile ligand for synthesizing transition metal complexes (e.g., Ni(II)), particularly in DNA interaction studies. These complexes demonstrate intercalation properties with binding constants up to 9.154×105 M-1.
Pharmaceutical Intermediates
Used in the synthesis of Schiff base derivatives for antimicrobial research, showing measurable inhibition against bacterial strains at experimental concentrations.
Analytical Reagent
Employed in chelation-based detection methods due to its selective binding with metal ions.
Research Case Studies
DNA-Binding Complex Development
A 2024 study utilized this compound to create Ni(II) complexes for analyzing DNA interaction mechanisms. Results confirmed strong intercalative binding via UV-vis spectroscopy and viscosity measurements.
Antimicrobial Agent Synthesis
Researchers synthesized 1,2,4-triazole Schiff base derivatives using 8-hydroxyquinoline-2-carboxaldehyde, achieving notable bactericidal activity at 50 μg/mL concentrations.
Client Success Stories
Nanjing Xiaozhuang University
Project: Development of eco-friendly antifungal agents
Outcome: Synthesized derivatives reduced fungal growth by 78% in agricultural trials.
Advanced Materials Research Lab
Project: Fluorescent sensor design for heavy metal detection
Outcome: Achieved 0.1 ppm detection limits for Cu(II) ions in aqueous systems.
PharmaTech Innovations
Project: Antibacterial drug candidate optimization
Outcome: Enhanced compound stability by 40% compared to previous formulations.
Request Quotation
Custom Synthesis & Bulk Orders
Available in research-grade (98% purity) and technical-grade quantities. MOQ: 5g.
Lead Time: 2–3 weeks for standard orders
Certifications: COA, NMR, HPLC, and MS provided
Contact Our Experts
Email: info@vivalr.com
Phone: (86) 15866781826
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