1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one (CAS 6704-31-0) is a high-purity heterocyclic compound with molecular formula C6H4N4O. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99.5% | 98.0% | 97.5% |
| Solubility | DMSO, DMF | Partial solubility | Limited solubility |
| Storage | 2-8°C, dry | Room temperature | 4-10°C |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Essential for synthesizing antiviral agents and kinase inhibitors, particularly in:
- HIV protease inhibitor development
- JAK/STAT signaling pathway modulators
Material Science Applications
- Coordination chemistry: Forms stable complexes with transition metals
- Organic electronics: Charge-transport layer component
3. Performance Comparison
| Feature | Our Product | Industry Standard |
|---|---|---|
| Reaction Yield | 92-95% | 85-88% |
| Thermal Stability | Up to 220°C | 200°C |
4. Industry Case Studies
Case 1: Antiviral Drug Development
Challenge: Improve synthesis efficiency of remdesivir analogs
Solution: Used as key intermediate in nucleoside phosphoramidate synthesis
Result: 40% reduction in synthesis steps
Case 2: OLED Manufacturing
Implemented as electron-transport material in blue-emitting devices, achieving 18% EQE improvement.
5. Customer Success Stories
PharmaGen Solutions (USA)
“Achieved 99.7% purity in GMP-grade production batches, accelerating our IND submission timeline by 6 months.”
AgroChem Innovations (Germany)
“Enabled development of novel fungicides with 3x longer residual activity compared to triazole alternatives.”
6. Request Customized Solutions
Contact our technical team for batch-specific COA, custom synthesis, or formulation support:


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