8-Hydroxyquinoline-2-carboxaldehyde

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Table of Contents

Basic Information & Specifications

Chemical Profile

Parameter Value
IUPAC Name 8-Hydroxyquinoline-2-carboxaldehyde
CAS Number 14510-06-6
Molecular Formula C10H7NO2
Molecular Weight 173.16 g/mol
Appearance Yellow crystalline powder
Melting Point 97–100°C
Boiling Point 392.2°C at 760 mmHg
Flash Point 191°C

Safety Data

Hazard Code Risk Statements Safety Precautions
Xi H315/H319/H335 P261, P305+P351+P338

Key Applications & Industrial Uses

Coordination Chemistry

Acts as a versatile ligand for synthesizing transition metal complexes (e.g., Ni(II)), particularly in DNA interaction studies. These complexes demonstrate intercalation properties with binding constants up to 9.154×105 M-1.

Pharmaceutical Intermediates

Used in the synthesis of Schiff base derivatives for antimicrobial research, showing measurable inhibition against bacterial strains at experimental concentrations.

Analytical Reagent

Employed in chelation-based detection methods due to its selective binding with metal ions.

Research Case Studies

DNA-Binding Complex Development

A 2024 study utilized this compound to create Ni(II) complexes for analyzing DNA interaction mechanisms. Results confirmed strong intercalative binding via UV-vis spectroscopy and viscosity measurements.

Antimicrobial Agent Synthesis

Researchers synthesized 1,2,4-triazole Schiff base derivatives using 8-hydroxyquinoline-2-carboxaldehyde, achieving notable bactericidal activity at 50 μg/mL concentrations.

Client Success Stories

Nanjing Xiaozhuang University

Project: Development of eco-friendly antifungal agents
Outcome: Synthesized derivatives reduced fungal growth by 78% in agricultural trials.

Advanced Materials Research Lab

Project: Fluorescent sensor design for heavy metal detection
Outcome: Achieved 0.1 ppm detection limits for Cu(II) ions in aqueous systems.

PharmaTech Innovations

Project: Antibacterial drug candidate optimization
Outcome: Enhanced compound stability by 40% compared to previous formulations.

Request Quotation

Custom Synthesis & Bulk Orders

Available in research-grade (98% purity) and technical-grade quantities. MOQ: 5g.
Lead Time: 2–3 weeks for standard orders
Certifications: COA, NMR, HPLC, and MS provided

Contact Our Experts

Email: info@vivalr.com
Phone: (86) 15866781826
Office Hours: Mon-Fri 8:30 AM–5:30 PM CST

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