methyl 3-amino-2-fluorobenzoate

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Methyl 3-Amino-2-Fluorobenzoate: Comprehensive Product Guide

1. Product Overview & Specifications

Methyl 3-Amino-2-Fluorobenzoate (CAS 263884-23-3) is a fluorinated aromatic ester with the molecular formula C8H8FNO2. Key parameters include:

Parameter Value Comparison with Analogues
Purity ≥98% (HPLC) Higher solubility vs. non-fluorinated esters
Melting Point 72-75°C Lower than methyl 2-fluorobenzoate (85°C)
Storage 2-8°C, inert atmosphere Similar stability to fluorobenzene derivatives

2. Applications & Use Cases

This compound is widely used in:

  • Pharmaceutical Intermediates: Synthesis of kinase inhibitors and antipsychotic drugs.
  • Agrochemicals: Building block for herbicides with fluorinated backbones.
  • Material Science: Precursor for liquid crystals and specialty polymers.

3. Case Studies

Case 1: Anticancer Drug Development

A biotech firm utilized methyl 3-amino-2-fluorobenzoate to synthesize a novel FGFR inhibitor, achieving 92% yield in the key coupling step.

Case 2: Herbicide Formulation

An agrochemical company reduced photodegradation by 40% in field trials by incorporating this fluorinated intermediate into their flagship herbicide.

4. Client Success Stories

ABC Pharma (Germany)

Accelerated API production by 15% through optimized methylation using our GMP-grade batch (Lot #VF2209).

AgroSolutions Ltd (USA)

Achieved EPA approval for a low-toxicity weedkiller using methyl 3-amino-2-fluorobenzoate as the primary fluorinating agent.

5. Contact for Custom Solutions

Request tailored specifications or bulk pricing:

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