2-Bromo-5-phenylthiophene: Ultimate User Guide
Table of Contents
- Product Overview & Specifications
- Applications & Industrial Uses
- Usage Scenarios & Case Studies
- Technical Comparison Table
- Client Success Stories
- Inquiry & Custom Solutions
Product Specifications
| Parameter | Value |
|---|---|
| Chemical Formula | C10H7BrS |
| CAS Number | 102113-98-4 |
| Molecular Weight | 239.13 g/mol |
| Appearance | Off-white crystalline powder |
| Purity | >98% (HPLC) |
| Melting Point | 78-82°C |
| Storage | 2-8°C in airtight container |
Key Applications
Pharmaceutical Intermediates
Critical building block for kinase inhibitors and anticancer agents. Enables precise bromine-directed cross-coupling reactions.
Organic Electronics
Essential monomer for conjugated polymers in OLEDs and OFETs. Enhances charge transport properties through thiophene ring modification.
Agrochemical Synthesis
Used in development of advanced fungicides with improved environmental stability.
Usage Scenarios
Case 1: Suzuki-Miyaura Coupling
Typical reaction conditions:
– Catalyst: Pd(PPh3)4 (2 mol%)
– Base: K2CO3 (2 eq)
– Solvent: THF/H2O (3:1)
Yield: 85-92% after purification
Case 2: Polymer Synthesis
Stille polycondensation with distannylated comonomers produces materials with:
– Bandgap: 2.1-2.3 eV
– Hole mobility: 10-3 cm²/V·s
Technical Comparison
| Property | 2-Bromo-5-phenylthiophene | 2-Bromo-thiophene | 5-Phenylthiophene |
|---|---|---|---|
| Reactivity | High (dual functionalization) | Moderate | Low |
| Thermal Stability | Up to 200°C | 180°C | 220°C |
| Solubility | THF, DCM, DMF | Ether, THF | Toluene |
Client Success Stories
PharmaTech Solutions
Challenge: Needed high-purity intermediate for Phase III clinical trial material
Solution: Custom synthesis at 99.5% purity with strict particle size control
Result: Achieved 40% yield improvement vs previous supplier
MaterialScience Inc.
Application: Developing flexible OLED displays
Outcome: Created polymer with 18% higher luminous efficiency
Volume: 50kg/month contract for R&D scale production
Request Custom Solutions
Our advantages:
– Batch-to-batch consistency (RSD <0.8%)
– Technical support from PhD chemists
– Global logistics compliance
Contact our team:
Email: info@vivalr.com
Tel: (86) 15866781826


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