2-Fluoropyridine-5-carboxaldehyde

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2-Fluoropyridine-5-carboxaldehyde: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

2-Fluoropyridine-5-carboxaldehyde (CAS 1072-97-5) is a fluorinated pyridine derivative widely used in pharmaceuticals, agrochemicals, and material science. Key specifications:

Parameter Value
Molecular Formula C₆H₄FNO
Molecular Weight 125.10 g/mol
Appearance Pale yellow crystalline powder
Purity ≥98% (HPLC)
Melting Point 72-75°C
Storage 2-8°C in airtight container

2. Applications & Use Cases

Pharmaceutical Intermediates

  • Synthesis of kinase inhibitors for cancer therapy
  • Building block for antiviral drug candidates

Agrochemicals

  • Key precursor for fungicides and herbicides

Material Science

  • Ligand in metal-organic frameworks (MOFs)

3. Comparative Analysis

Supplier Purity Packaging Price (USD/g)
Supplier A 98% 1g, 5g $85
Supplier B 99% 5g, 25g $92
Supplier C 97% 10g, 50g $78

4. Usage Guidelines

Handling Precautions

  • Use PPE: gloves, goggles, and lab coat
  • Operate under fume hood

Synthetic Protocols

  • Suzuki-Miyaura coupling: 0.1 mol% Pd catalyst, 80°C, 12h
  • Aldoxime formation: NH₂OH·HCl, EtOH, reflux

5. Customer Case Studies

Case 1: Anticancer Drug Development

  • Client: European Pharma Co.
  • Challenge: Low yield in kinase inhibitor synthesis
  • Solution: Optimized fluoropyridine coupling using 2-Fluoropyridine-5-carboxaldehyde
  • Result: Yield increased from 45% to 78%

Case 2: Agrochemical Intermediate

  • Client: Asia Agro Ltd.
  • Challenge: Impurity control in fungicide precursor
  • Solution: Implemented HPLC-purified 2-Fluoropyridine-5-carboxaldehyde
  • Result: Achieved 99.5% purity in final product

6. Contact for Inquiries

Request custom synthesis, bulk pricing, or technical support:

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