5-Nitropyridine-2-carboxylic acid

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Comprehensive Guide to 5-Nitropyridine-2-carboxylic Acid

Table of Contents

1. Basic Information & Specifications

Parameter 5-Nitropyridine-2-carboxylic Acid Comparable Compounds
CAS Number 5345-47-1 2-Chloropyridine-5-carboxylic acid (37439-34-2)
Molecular Formula C6H4N2O4 C6H4ClNO2
Purity >98% >95%
Melting Point 220-223°C 195-198°C
Solubility Soluble in DMSO, Methanol Soluble in Chloroform

2. Detailed Applications

Pharmaceutical Intermediates

Critical precursor for kinase inhibitors (e.g., EGFR inhibitors) and antibiotic drug candidates.

Agrochemical Synthesis

Used in herbicides/pesticides targeting nicotinic acetylcholine receptors.

Material Science

Ligand in metal-organic frameworks (MOFs) for catalytic applications.

3. Industry Use Cases

Case 1: Anticancer Drug Development

Modified to create prodrugs with 3x higher bioavailability in preclinical trials.

Case 2: Next-Gen Insecticides

Key intermediate in neonicotinoid analogs with reduced bee toxicity.

4. Client Success Stories

Client A: European Pharma Leader

Scaled production to 50kg/month for Phase II oncology trials with 99.2% purity.

Client B: US Agrochemical Innovator

Developed patent-pending fungicide using custom nitration services.

5. Purchasing Guide

Key Parameters

  • HPLC purity ≥98% (USP/EP standards)
  • Residual solvent: <500ppm

Supplier Qualifications

  • ISO 9001:2015 certification
  • REACH compliance documentation

6. Contact for Quotation

Email: info@vivalr.com
Tel: (86) 15866781826

Sample Quotation Request

Required: 5-Nitropyridine-2-carboxylic acid, 10kg, HPLC ≥98%
Delivery: DDP Incoterms 2020 to Frankfurt
Deadline: Submit COA and stability data by 2025-03-25

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