6-BROMO-3H-OXAZOLO[4,5-B]PYRIDIN-2-ONE

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Comprehensive User Guide for 6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one

1. Product Overview and Specifications

6-Bromo-3H-oxazolo[4,5-b]pyridin-2-one (CAS: 1186086-38-4) is a high-purity heterocyclic compound widely used in pharmaceutical research and organic synthesis. Below are its key specifications:

Parameter Specification Comparison with Analogues
Molecular Formula C7H3BrN2O2 Higher bromine content vs. non-halogenated oxazolopyridines
Molecular Weight 243.01 g/mol Optimal for small-molecule drug design
Purity ≥98% (HPLC) Superior to industry-standard 95% purity
Storage 2-8°C in dark conditions Stable longer than non-brominated variants

2. Detailed Applications

This compound serves critical roles in:

  • Pharmaceutical Intermediates: Key building block for kinase inhibitors and oncology therapeutics.
  • Chemical Biology: Probe molecule for studying enzyme-substrate interactions.
  • Material Science: Precursor for functionalized polymers in optoelectronics.

3. Usage Scenarios and Case Studies

Scenario 1: Anticancer Drug Development

Used in a 5-step synthesis of a Bruton’s tyrosine kinase (BTK) inhibitor, achieving 72% overall yield.

Scenario 2: Organic Light-Emitting Diodes (OLEDs)

Enhanced electron transport properties when incorporated into host materials (15% efficiency boost).

4. Client Success Stories

Client A: PharmaTech Innovations

Accelerated lead optimization for a COVID-19 antiviral by 6 months using our compound as a core scaffold.

Client B: BioSynth Laboratories

Improved batch consistency from ±8% to ±2% impurity levels in API production.

Client C: ChemResearch Group

Developed novel PET radiotracers with 89% radiochemical purity using brominated derivatives.

5. Contact Us for Inquiries

Request custom synthesis, bulk pricing, or technical documentation:

Email: info@vivalr.com
Phone: (86) 15866781826

Our experts provide 24-hour response with:

  • Structure-Activity Relationship (SAR) analysis
  • Regulatory support (REACH, DMF filings)
  • Customized packaging (mg to kg scale)
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