BOC-D-Arginine Hydrochloride Monohydrate (CAS 114622-81-0) Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | BOC-D-Arginine HCl·H₂O | BOC-L-Arginine HCl·H₂O | DL-Arginine HCl·H₂O |
|---|---|---|---|
| CAS Number | 114622-81-0 | 137076-54-1 | 32042-43-6 |
| Molecular Formula | C₁₁H₂₅ClN₄O₅ | C₁₁H₂₅ClN₄O₅ | C₆H₁₄N₄O₂·HCl·H₂O |
| Optical Rotation | [α]D²⁰ = +12° to +14° | [α]D²⁰ = -12° to -14° | Racemic mixture |
| Pharma Applications | Antiviral intermediates Enzyme inhibitors |
Cardiovascular drugs Wound healing |
Nutritional supplements Cosmetic formulations |
2. Functional Applications
Peptide Synthesis: Serves as critical amino acid protector in solid-phase peptide synthesis (SPPS) with 98.5% coupling efficiency.
Pharmaceutical Intermediates: Key building block for protease inhibitors and anticoagulant agents.
Biochemical Research: Used in chiral resolution studies and enzyme-substrate interaction analysis.
3. Operational Guidelines
Storage: Maintain at 2-8°C in nitrogen atmosphere with ≤30% relative humidity.
Solubility: 50 mg/mL in DMSO (clear solution at 25°C)
Handling: Use nitrile gloves and chemical splash goggles in controlled environment
4. Industrial Case Studies
Case 1: Antiviral Drug Development
Client: Top 10 Global Pharma Company
Application: COVID-19 protease inhibitor R&D
Result: Achieved 73% viral replication inhibition at 50μM concentration
Case 2: Diagnostic Reagent Production
Client: IVD Manufacturer (Germany)
Application: ELISA kit component for autoimmune diseases
Result: Enhanced assay sensitivity by 40% vs conventional reagents
5. Procurement Consultation
Available specifications: 1g, 5g, 25g, 100g (GMP-grade upon request)
Global shipping via DHL/FedEx with temperature-controlled packaging
Technical support: MSDS, COA, NMR/HPLC reports provided
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