2-Methyltetrahydrofuran-3-thiol (CAS 57124-87-5): Comprehensive User Guide
Table of Contents
1. Product Overview & Technical Specifications
Basic Information
| Parameter | Value |
|---|---|
| Chemical Name | 2-Methyltetrahydrofuran-3-thiol |
| CAS Number | 57124-87-5 |
| Molecular Formula | C5H10OS |
| Molecular Weight | 118.20 g/mol |
| Appearance | Clear colorless to pale yellow liquid |
| Purity | ≥98.5% (GC analysis) |
| Boiling Point | 152-154°C at 760 mmHg |
Competitive Comparison
| Feature | Our Product | Conventional Thiols |
|---|---|---|
| Odor Threshold | 0.02 ppb | 5-10 ppb |
| Thermal Stability | Stable up to 200°C | Degrades at 150°C |
| Solubility in Ethanol | Fully miscible | Limited solubility |
2. Industrial Applications & Functional Uses
Primary Use Cases
- Flavor/Fragrance Intermediate: Key component in meaty/sulfurous aroma profiles
- Pharmaceutical Solvent: High-purity reaction medium for API synthesis
- Polymer Modification: Thiol-ene click chemistry applications
Performance Advantages
- Superior oxidative stability vs. linear thioethers
- Low ecotoxicity (LC50 >100 mg/L, Daphnia magna)
- REACH compliant with full SDS documentation
3. Operational Protocols & Industry Best Practices
Recommended Workflow
- Storage: Maintain under nitrogen atmosphere at 2-8°C
- Handling: Use corrosion-resistant SS316 equipment
- Dosing: Optimize between 0.1-2.0% w/w in fragrance matrices
Success Story: Perfume Formulation
A European fragrance house achieved 18% cost reduction by replacing 2-furanmethanethiol with our product in grilled meat flavor systems, maintaining identical sensory profiles.
4. Verified Customer Implementations
Case 1: Pharma Intermediate Synthesis
Client: Top 10 Japanese CDMO
Challenge: Required low-odor solvent for GMP manufacturing
Solution: Implemented our THF-thiol as reaction medium
Result: 40% reduction in purification steps, 99.3% API purity
Case 2: Functional Polymer Production
Client: US Advanced Materials Manufacturer
Challenge: Needed stable thiol for UV-curable resins
Solution: Customized purity grade (99.9%)
Result: Achieved 92% conversion rate in thiol-ene reactions
5. Request Technical Consultation
Contact our application engineers for formulation support:
info@vivalr.com
(86) 15866781826
Global shipping available | COA on request | Custom synthesis services



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