Chemical Name: 3′-Hydroxyacetophenone
Synonyms: m-Hydroxyacetophenone; 3-Acetylphenol; m-Acetylphenol; Rivastigmine Impurity 4; 3-Acetophenol; 3-Hydroxyphenyl methyl ketone; m-Hydroxyacetophenone; M-hydroxyacetone; 5-Hydroxy Acetophenone
CAS No.: 121-71-1
Molecular Fomula: C14H12ClN
Parameter | 3′-Hydroxyacetophenone | 2′-Hydroxyacetophenone | 4′-Hydroxyacetophenone |
---|---|---|---|
CAS Number | 121-71-1 | 118-93-4 | 99-93-4 |
Molecular Formula | C8H8O2 | C8H8O2 | C8H8O2 |
Purity | ≥99% | ≥98% | ≥99.5% |
Melting Point | 96-98°C | 108-110°C | 109-112°C |
Widely used in synthesis of β-blocker drugs and antispasmodic agents. The hydroxyl group enables crucial coupling reactions in API production.
Key precursor for:
Temperature | 2-8°C |
Humidity | ≤30% RH |
Light Sensitivity | Store in amber glass |
A European API manufacturer achieved 22% yield improvement in atenolol synthesis through optimized recrystallization techniques using our 3′-Hydroxyacetophenone.
Japanese electronics company developed novel liquid crystal materials with enhanced thermal stability using this compound as alignment layer precursor.
Challenge | Impurity control in β-blocker synthesis |
Solution | Implemented our HPLC-validated 3′-Hydroxyacetophenone |
Result | Reduced side products by 38% |
Application | Benzofuran derivative production |
Volume | 2.5MT/month continuous supply |
Benefit | 99.2% consistent purity over 18 months |
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