Diphenyl Phosphite (CAS 4712-55-4) Comprehensive User Guide
Table of Contents
1. Product Overview & Technical Specifications
Diphenyl Phosphite (CAS 4712-55-4) is an organophosphorus compound with the molecular formula C12H11O3P and molecular weight 234.19 g/mol. It appears as a clear to pale yellow liquid with a characteristic odor.
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥95% | 90-92% | 85-88% |
| Storage | 2-8°C (under N2) | Ambient | Ambient |
| Packaging | 25kg drums/100g samples | 50kg only | No sample sizes |
2. Key Applications & Industrial Uses
- Coupling Agent: Enables synthesis of esters and amides under mild conditions
- Peptide Bond Formation: Facilitates efficient amide coupling in pharmaceutical intermediates
- Olefin Synthesis: Mediates alkyl halide-aldehyde reactions for alkene production
- Catalytic Reactions: Participates in C-C/C-N bond additions with transition metal catalysts
- Ring Formation: Activates nucleophilic centers for cyclic compound synthesis
3. Operational Guidelines & Best Practices
Safety Protocols
| Hazard | Precaution |
|---|---|
| Skin Irritation (Category 2) | Wear nitrile gloves & chemical apron |
| Eye Damage (Category 1) | Use sealed goggles & face shield |
| Respiratory Irritation | Implement fume hood ventilation ≥0.5 m/s |
4. Case Studies & Real-World Implementations
Pharmaceutical Intermediate Synthesis
A leading API manufacturer achieved 92% yield improvement in atorvastatin intermediate production through optimized diphenyl phosphite-mediated coupling.
5. Client Success Stories
Case 1: Specialty Polymer Development
Shanghai ChemTech Co. reduced polymerization side reactions by 40% using our high-purity (99.2%) diphenyl phosphite in flame-retardant polycarbonate production.
Case 2: Agricultural Chemical Synthesis
Wuhan AgroScience reported 30% cost reduction in herbicide intermediate manufacturing through our bulk supply program.
6. Request Customized Solutions
Contact our technical team for application-specific support:
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