Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Use Cases
- 3. Industry Case Studies
- 4. Handling & Safety Guidelines
- 5. Request Customized Quotes
1. Product Overview & Specifications
4-(2-Bromoacetyl)benzonitrile (CAS 20099-89-2)
| Parameter | Specification | Comparison with Similar Compounds |
|---|---|---|
| Molecular Formula | C9H5BrNO | Higher reactivity vs. chloroacetyl analogs |
| Molecular Weight | 223.05 g/mol | Optimal for small-molecule synthesis |
| Appearance | White to off-white crystalline powder | Superior purity (≥98%) vs. standard grades |
| Melting Point | 98-102°C | Stable under ambient conditions |
| Storage | 2-8°C in inert atmosphere | Longer shelf-life than bromoacetophenone derivatives |
2. Key Applications & Use Cases
Pharmaceutical Intermediate
Widely used in synthesis of kinase inhibitors and anticancer agents due to its dual functional groups enabling:
- Nucleophilic substitution reactions
- Suzuki-Miyaura cross-coupling
- Cyclization reactions for heterocyclic systems
Agrochemical Development
Critical component in creating novel pesticides through:
- Acetyl group bromination for targeted activity
- Cyanobenzene moiety for enhanced stability
3. Industry Case Studies
Case Study 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesis of third-generation EGFR inhibitors
Result: 22% yield improvement vs. traditional bromoketone intermediates
Case Study 2: Agricultural Research
Client: EU-based Agrochemical Innovator
Application: Development of systemic fungicides
Result: Achieved 99.7% enantiomeric purity in final product
4. Handling & Safety Guidelines
| Parameter | Requirement |
|---|---|
| Personal Protection | Nitrile gloves, chemical goggles |
| Ventilation | Local exhaust required |
| Incompatibilities | Strong bases, oxidizing agents |
| Spill Management | Absorb with vermiculite, pH-neutralize |
5. Request Customized Quotes
Our technical team provides:
- Custom synthesis services (gram to kilogram scale)
- GMP-grade production capabilities
- Regulatory support for FDA/EMA submissions
Contact our specialists for formulation advice:
Email: info@vivalr.com
Phone: (86) 15866781826



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