Lithium Tetrachlorocuprate CAS 15489-27-7

Lithium Tetrachlorocuprate (CAS 15489-27-7) Comprehensive Guide

Table of Contents

• Basic Information & Specifications
• Detailed Applications
• Usage Guidelines
• Case Studies
• Contact for Quotation

Basic Information & Specifications

Supplier Comparison

Detailed Applications

Lithium Tetrachlorocuprate is primarily utilized in organic synthesis for cross-coupling reactions, particularly between Grignard reagents and bromoalkanes or tosylates. Its catalytic properties enable efficient carbon-carbon bond formation, critical in:

• Pharmaceutical intermediates production
• Advanced material synthesis
• Fine chemical manufacturing

Usage Guidelines

Handling Precautions

• Store in flammable storage area at 2-8°C
• Use under inert gas atmosphere (N₂ or Ar)
• Moisture-sensitive: maintain anhydrous conditions

Reaction Setup Example

Cross-Coupling Protocol:
1. Charge reactor with 0.1M Lithium Tetrachlorocuprate/THF solution (2 eq)
2. Add Grignard reagent (1.2 eq) at -20°C
3. Introduce bromoalkane substrate (1 eq) gradually
4. Warm to room temperature and stir for 12h

Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

Client: Shanghai Medichem Research Institute
Application: Synthesis of kinase inhibitor intermediate
Result: 78% yield improvement vs. traditional catalysts

Case 2: Electronic Material Production

Client: Shenzhen Advanced Materials Co., Ltd.
Application: Conductive polymer chain elongation
Result: Achieved 92% regioselectivity

Contact for Quotation

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