2-Bromo-9,9-dimethylfluorene CAS 28320-31-2

Chemical Name: 2-Bromo-9,9-dimethylfluorene
CAS No.: 28320-31-2
Molecular Fomula: C15H13Br
Molecular weight: 273.17
Appearance: White powder
Assay: ≥99%

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2-Bromo-9,9-dimethylfluorene (CAS 28320-31-2): Comprehensive User Guide

1. Product Overview & Specifications

1.1 Chemical Profile

2-Bromo-9,9-dimethylfluorene (CAS 28320-31-2) is a brominated fluorene derivative with a molecular formula of C15H13Br. This organobromine compound features a dimethyl-substituted fluorene backbone, making it a critical intermediate in advanced organic synthesis.

1.2 Key Specifications

Parameter Specification 2-Bromofluorene 9,9-Dimethylfluorene
Molecular Weight 273.17 g/mol 245.08 g/mol 208.26 g/mol
Melting Point 98-102°C 153-155°C 185-187°C
Thermal Stability Excellent Moderate High

*Comparative data highlights enhanced stability and reactivity vs. similar compounds.

2. Key Applications & Use Cases

2.1 OLED Material Synthesis

Widely used as a precursor for hole-transport layers (HTL) in OLED displays. The dimethyl groups improve electron mobility while the bromine atom enables efficient cross-coupling reactions.

2.2 Pharmaceutical Intermediates

Essential in synthesizing kinase inhibitors and anticancer agents. The bromine site facilitates Suzuki-Miyaura couplings for biaryl drug candidates.

2.3 Polymer Additives

Enhances thermal stability in engineering plastics when incorporated into polyfluorene backbones at 0.5-2% w/w concentrations.

3. Industry Case Studies

3.1 OLED Manufacturer Case

Client: TechNova Displays (Shenzhen)
Challenge: Required a HTL material with ≥90% luminous efficiency at 150°C.
Solution: Synthesized customized derivatives using 2-Bromo-9,9-dimethylfluorene.
Result: Achieved 92% efficiency with 15% lower power consumption.

3.2 Pharmaceutical Research Case

Client: BioGen Therapeutics (Boston)
Challenge: Needed scalable synthesis of a BTK inhibitor intermediate.
Solution: Optimized Buchwald-Hartwig amination using our compound.
Result: Reduced reaction steps from 5 to 3, achieving 85% yield at kilo-scale.

4. Technical Support & Inquiry

Our team provides:

  • Custom synthesis (purity 98-99.9%)
  • Technical documentation (CoA, MSDS)
  • Process optimization support

Contact for Pricing/Samples:
Email: info@vivalr.com
Phone: (86) 15866781826

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