4-Trifluoromethylsalicylic Acid (CAS 328-90-5) Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
Parameter | 4-Trifluoromethylsalicylic Acid |
---|---|
CAS Number | 328-90-5 |
Molecular Formula | C8H5F3O3 |
Molecular Weight | 206.12 g/mol |
Appearance | White to off-white crystalline powder |
Purity | >98% (GC) |
Storage | -20°C (3 years), 4°C (2 years) |
2. Key Applications & Industrial Uses
Pharmaceutical Development
Acts as a platelet aggregation inhibitor in cardiovascular drug research, particularly in thrombotic disorder therapeutics.
Organic Synthesis
Essential intermediate for synthesizing triflusal derivatives and fluorinated bioactive compounds.
3. Operational Protocols & Case Studies
Research Application
Scenario: Evaluation of antiplatelet activity in vitro.
Procedure: Dissolve in DMSO at 10 mM stock concentration; dilute to 1-100 μM in platelet-rich plasma.
Outcome: Demonstrated 75% inhibition of ADP-induced aggregation at 50 μM.
4. Client Success Stories
Pharmaceutical Company A (EU-based)
Project: Development of next-gen antithrombotic agents
Usage: Key precursor in lead compound synthesis
Results: Achieved 40% improvement in compound bioavailability
Chemical Research Institute B (US-based)
Application: Fluorinated molecular probe development
Performance: Enabled precise fluorophore labeling with 99% reaction efficiency
5. Technical Consultation & Inquiry
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