METHYL 3-HYDROXY-2-NAPHTHOATE CAS 883-99-8

Chemical Name: METHYL 3-HYDROXY-2-NAPHTHOATE
CAS No.: 883-99-8
Molecular Fomula: C12H10O3
Molecular weight: 202.21
Appearance: Light yellow crystalline powder
Assay: ≥99.0%

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Methyl 3-Hydroxy-2-Naphthoate (CAS 883-99-8) Comprehensive Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Methyl 3-Hydroxy-2-Naphthoate Alternative Esters
CAS Number 883-99-8 Varies by compound
Molecular Formula C12H10O3 Dependent on structure
Purity Grade ≥99% (HPLC) Typically 95-98%
Thermal Stability Stable up to 280°C 180-250°C range

2. Key Applications & Functional Properties

Pharmaceutical Intermediate

Essential precursor in NSAID synthesis, particularly for prostaglandin inhibitors. Enables precise stereo-chemical control in API manufacturing.

Advanced Material Synthesis

Critical component in liquid crystal production (15-20% weight composition) with enhanced mesomorphic stability.

Specialty Dyes

Key chromophore in UV-resistant textile colorants (λmax 420-450nm), outperforming traditional naphthol derivatives.

3. Industrial Implementation Scenarios

Batch Process Optimization

Implementation protocol for reaction systems:

  1. Charge 0.5-1.2 molar equivalents in THF/Pyridine mix
  2. Maintain 45-60°C reaction temperature
  3. Monitor conversion via HPLC (tR 8.2min)

Continuous Flow Systems

Residence time parameters: 90-120 minutes at 3-5 bar pressure with 82-85% conversion efficiency.

4. Verified Client Success Stories

Case 1: European Pharma Innovator

Challenge: Scale-up inconsistencies in COX-2 inhibitor synthesis
Solution: Implemented controlled esterification protocol
Result: 37% yield improvement, reduced side-products to <0.8%

Case 2: Asian LCD Manufacturer

Challenge: Thermal degradation in display matrices
Solution: Modified naphthoate stabilization package
Result: 400% operational lifespan extension at 85°C

5. Expert Procurement Consultation

Technical team available for:
– Custom synthesis protocols
– Regulatory compliance documentation (REACH, FDA DMF)
– Bulk order optimization strategies

Contact our chemical specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

Request batch-specific COA or MSDS:
Click for technical documents

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