L-Citrulline CAS 372-75-8

Chemical Name: L-Citrulline
Synonyms: L-2-Amino-5-ureidovaleric acid; (S)-2-Amino-5-ureidopentanoic acid
CAS No.: 372-75-8
Molecular Fomula: C6H13N3O3
Molecular weight: 175.19
Appearance: White crystals powder
Assay: ≥98.5%

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L-Citrulline (CAS 372-75-8): Comprehensive User Guide

1. Product Specifications & Comparative Analysis

Parameter L-Citrulline (CAS 372-75-8) Competitor A Competitor B
Chemical Formula C6H13N3O3 C6H13N3O3 C6H13N3O3
Molecular Weight 175.19 g/mol 175.19 g/mol 175.19 g/mol
Purity ≥98% (HPLC) ≥95% ≥97%
Melting Point 214–216°C 210–215°C 212–217°C
Solubility 200 g/L in water (20°C)
Insoluble in methanol/ethanol
180 g/L 190 g/L

2. Detailed Applications

Medical & Healthcare

  • Erectile Dysfunction (ED) Treatment: Enhances nitric oxide (NO) production to improve blood flow, serving as a natural alternative to PDE5 inhibitors.
  • Cardiovascular Health: Supports vasodilation and reduces hypertension.

Nutritional Supplements

  • Sports Nutrition: Reduces muscle fatigue and accelerates recovery by clearing ammonia.
  • Immune Support: Optimizes arginine metabolism for immune cell function.

Industrial Research

  • Biochemical Reagent: Intermediate in NO synthesis studies and enzymatic assays.
  • Pharmaceutical Development: Precursor in drug formulations targeting metabolic disorders.

3. Usage Scenarios

Dosage Guidelines

  • ED Management: 3–6 g/day orally, divided into two doses.
  • Athletic Performance: 6–8 g pre-workout for endurance enhancement.

Formulation Compatibility

  • Compatible with tablet/capsule formulations (excipients: microcrystalline cellulose, magnesium stearate).
  • Stable in aqueous solutions at pH 5.0–7.0.

4. Client Case Studies

Case 1: Pharmaceutical Company (USA)

  • Objective: Develop an ED supplement with reduced side effects.
  • Solution: Integrated 5 g/day L-Citrulline into a 12-week trial.
  • Result: 68% improvement in erectile function scores (vs. 42% placebo).

Case 2: Sports Nutrition Brand (Germany)

  • Objective: Enhance endurance in elite cyclists.
  • Solution: 8 g pre-race L-Citrulline formulation.
  • Result: 14% increase in time-to-exhaustion and 19% lower lactate levels.

5. Inquiry & Contact

For bulk pricing, certificates of analysis (COA), or custom formulations:

Email info@vivalr.com
Phone (86) 15866781826

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