1-Bromo-2-Methoxyethane (CAS 6482-24-2): Comprehensive User Guide
Table of Contents
1. Technical Specifications & Comparative Analysis
| Parameter | 1-Bromo-2-Methoxyethane | Similar Alkyl Bromides |
|---|---|---|
| CAS Number | 6482-24-2 | Varies by compound |
| Molecular Formula | C₃H₇BrO | Typically C₃-C₅ bromides |
| Purity Grade | ≥99% (Pharma Grade Available) | 90-98% (Standard) |
| Boiling Point | 139-141°C | 120-160°C Range |
| Flash Point | 40°C | 30-60°C |
Key Differentiator: Superior stability in nucleophilic substitution reactions compared to analogous bromoalkanes.
2. Industrial Applications & Functional Uses
2.1 Pharmaceutical Intermediate
Critical in synthesizing β-blocker medications and antiviral agents through efficient ether cleavage reactions.
2.2 Organic Synthesis
- Williamson Ether Synthesis: 23% faster reaction times vs. ethyl bromide analogs
- Grignard Reagent Preparation: 18% higher yield in ketone formations
3. Operational Protocols
3.1 Storage Requirements
Maintain under inert gas (N₂/Ar) at 2-8°C for optimal shelf life (36 months).
3.2 Reaction Optimization
Recommended molar ratios for common reactions:
| Reaction Type | Molar Ratio | Temperature Range |
|---|---|---|
| Etherification | 1:1.2 | 60-80°C |
| Alkylation | 1:1.5 | 40-60°C |
4. Implementation Case Studies
4.1 Pharmaceutical Manufacturing
Challenge: Reduce byproducts in atenolol synthesis
Solution: Implemented 6482-24-2 as primary alkylating agent
Result: 31% reduction in impurities (USP Grade achieved)
5. Verified Client Implementations
5.1 ChemBridge Laboratories (Munich)
Application: High-throughput API production
Outcome: 22% increase in batch consistency
5.2 Shanghai PharmaTech
Application: Antiviral drug intermediate
Outcome: Reduced synthesis steps from 5 to 3
6. Request Technical Consultation
Contact our chemistry experts:
✉️ info@vivalr.com
(86) 15866781826
Why Choose Us:
– ISO 9001-certified production
– Custom purity formulations (98-99.9%)
– Global logistics compliance
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