Glycoursodeoxycholic Acid (CAS 64480-66-6) Ultimate Buyer’s Guide
Table of Contents
Product Overview
| Parameter | Specification |
|---|---|
| CAS Number | 64480-66-6 |
| Molecular Formula | C26H43NO5 |
| Appearance | White crystalline powder |
| Purity Grade | Pharmaceutical (≥98%)/Research (≥95%) |
| Storage Conditions | 2-8°C in airtight container |
Technical Specifications Comparison
| Compound | Solubility | Thermal Stability | Bioavailability |
|---|---|---|---|
| Glycoursodeoxycholic Acid | Water-soluble conjugate | Stable below 40°C | Enhanced absorption |
| Ursodeoxycholic Acid | Lipid-soluble | Degrades above 50°C | pH-dependent |
| Chenodeoxycholic Acid | Ethanol-soluble | Oxidizes in air | Variable metabolism |
Industrial & Research Applications
Pharmaceutical Development
- Primary bile acid replacement therapy
- Cholesterol gallstone dissolution agent
- Hepatoprotective formulations
Biochemical Research
- Cell membrane permeability studies
- Cholesterol homeostasis regulation
- Nuclear receptor activation assays
Industrial Applications
- Cosmetic emulsifying agents
- Food additive stabilization
- Diagnostic reagent formulation
Verified Usage Cases
Case Study 1: Hepatology Formulation Development
| Client Profile | EU-based Pharma Company (GMP Certified) |
|---|---|
| Application | Chronic cholestasis treatment formulation |
| Technical Requirements | ≥99% purity, endotoxin-free, crystalline structure verification |
| Outcome | Successful Phase II clinical trial completion |
Case Study 2: Academic Research Project
| Institution | North American University Research Lab |
|---|---|
| Study Focus | FXR receptor activation mechanisms |
| Material Specifications | HPLC-verified 97% purity, isotope-labeled variants |
| Publication | Published in Hepatology (Impact Factor 14.971) |
Strategic Procurement Guidance
- Verify analytical certificates (COA, MSDS, HPLC/GC reports)
- Request stability data for long-term storage
- Confirm regulatory compliance (REACH, USP, EP)
- Evaluate supplier quality systems (GMP vs. non-GMP)
- Compare batch-to-batch consistency guarantees
Contact for Technical Consultation
Request custom synthesis quantities or modified specifications:
- Email: info@vivalr.com
- Phone: (86) 15866781826
- Office Hours: Mon-Fri 08:00-17:00 (GMT+8)
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