Diethyl oxalacetate sodium salt CAS 40876-98-0

Directory

• 1. Product Overview & Specifications
• 2. Key Applications & Industrial Uses
• 3. Operational Guidelines & Best Practices
• 4. Implementation Case Studies
• 5. Verified Client Success Stories
• 6. Request Customized Quotation

Diethyl Oxalacetate Sodium Salt (CAS 40876-98-0) Technical Specifications

Comparative Analysis of Commercial Grades

Critical Quality Indicators

Molecular Formula: C₈H₁₁NaO₆
Molecular Weight: 234.16 g/mol
Appearance: White crystalline powder
Solubility: Water >50 mg/mL

Industrial Applications & Functional Advantages

Pharmaceutical Synthesis

Essential intermediate for:
– ACE inhibitor production
– Antiviral drug precursors
– Neurological active compounds

Biochemical Research

– Enzyme kinetics studies (malate dehydrogenase assays)
– Metabolic pathway analysis
– Cell culture media optimization

Organic Chemistry

– Stobbe condensation reactions
– Knoevenagel synthesis
– Asymmetric catalysis

Optimal Handling Protocols

Storage Recommendations

1. Maintain sealed containers under nitrogen atmosphere
2. Desiccate at ≤25°C
3. Avoid prolonged exposure to UV light

Reaction Optimization

– Ideal pH range: 6.8-7.4
– Temperature sensitivity: Decomposes above 150°C
– Compatible solvents: DMSO, ethanol, aqueous buffers

Implementation Scenarios

Pharmaceutical Manufacturing

Challenge: Scale-up of antihypertensive API
Solution: Implemented controlled esterification process
Outcome: 22% yield improvement vs traditional methods

Academic Research

Study: Mitochondrial metabolism analysis
Application: Real-time NADH monitoring substrate
Result: Published in Nature Cell Biology (2023)

Client Success Documentation

Case 1: EuroPharma Solutions

Industry: Generic Drug Manufacturing
Application: Continuous flow synthesis
Metrics: 98.7% purity achieved, 15% cost reduction

Case 2: Cambridge BioResearch

Research Focus: Cancer metabolism
Implementation: High-throughput screening
Outcome: Identified 3 novel enzyme inhibitors

Technical Consultation & Quotation

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