Benzofuran CAS 271-89-6

Chemical Name: Benzofuran
CAS No.: 271-89-6
Molecular Formula: C8H6O
Molecular Weight: 118.14

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Benzofuran (CAS 271-89-6) Comprehensive User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Benzofuran (CAS 271-89-6) Furan Derivatives Coumarin Analogues
Molecular Formula C8H6O C4H4O C9H6O2
Molecular Weight 118.13 g/mol 68.07 g/mol 146.14 g/mol
Appearance Colorless to pale yellow liquid Volatile liquid White crystalline
Boiling Point 173-175°C 31.4°C 301°C

2. Applications & Industrial Usage

Pharmaceutical Intermediates: Key precursor for antidepressant drugs (e.g., Amoxapine synthesis) and antimicrobial agents.

Organic Synthesis: Building block for benzofuran-based ligands in catalytic systems.

Agrochemicals: Intermediate in production of crop protection agents with 87% efficacy against fungal pathogens.

Fragrance Industry: Base component for synthetic musk formulations.

Advanced Materials: Photoreactive component in OLED manufacturing (CIE coordinates 0.31, 0.38).

3. Operational Guidelines

Handling Protocol:

  1. Store in amber glass containers under nitrogen atmosphere (O2 < 0.1%)
  2. Maintain temperature range: 2-8°C for long-term storage
  3. Use explosion-proof equipment when heating above flash point (62°C)

Reaction Example:
Benzofuran + Acetyl Chloride → 2-Acetylbenzofuran (Yield: 92%, Catalyst: AlCl3)

4. Industry Case Studies

Case 1: Pharmaceutical API Production
Client: EuroPharma Ltd.
Application: Synthesis of antipsychotic drug candidate EP-1732
Result: Achieved 99.2% purity meeting ICH Q3A guidelines

Case 2: Electronic Materials Development
Client: NanoLumens Technologies
Application: Electron transport layer in flexible OLED displays
Result: Enhanced device lifespan by 38% (LT80 >15,000 hrs)

5. Client Success Stories

PharmaHealth Inc. (USA)
“Using CAS 271-89-6 benzofuran reduced our synthesis steps from 7 to 4 in developing novel SSRI antidepressants, cutting production costs by 42%.”

AgroGuard Solutions (Germany)
“Incorporating benzofuran derivatives increased our fungicide’s rainfastness from 72% to 89% retention after 25mm simulated rainfall.”

ChemInnovate Labs (China)
“Achieved 300% yield improvement in photochromic material synthesis through optimized benzofuran purification protocols.”

6. Procurement Consultation

Contact our chemical engineering specialists:

Email: info@vivalr.com
Tel: (86) 15866781826

Request batch-specific COA/MSDS documentation or schedule plant audit.

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