Comprehensive Guide to Spermine (CAS 71-44-3)
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications of Spermine
- 3. Usage Guidelines
- 4. Case Studies
- 5. Client Success Stories
- 6. Request a Quote
1. Product Overview & Specifications
Spermine (CAS 71-44-3) is a naturally occurring polyamine critical for cellular metabolism and growth. Below are key specifications:
| Parameter | Value |
|---|---|
| CAS Number | 71-44-3 |
| Molecular Formula | C₁₀H₂₆N₄ |
| Molecular Weight | 202.34 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Water, ethanol, acidic solutions |
Comparative Analysis with Similar Compounds
| Compound | Function | Key Advantage of Spermine |
|---|---|---|
| Spermidine | Cell proliferation | Superior DNA stabilization |
| Putrescine | Basic metabolic processes | Enhanced antioxidant properties |
2. Applications of Spermine
Biomedical Research
- DNA/RNA precipitation in molecular biology protocols.
- Apoptosis regulation studies in cancer research.
Pharmaceuticals
- Intermediate in antiviral/antitumor drug synthesis.
- Enhancer for drug delivery systems.
Agriculture & Industrial
- Plant growth regulator for stress resistance.
- Additive in biopolymer production.
3. Usage Guidelines
Recommended Protocols
- DNA Precipitation: Use 5-10 mM final concentration in buffers.
- Cell Culture: Optimize at 1-5 µM to avoid cytotoxicity.
Safety & Handling
- Store at 2-8°C in airtight containers.
- Use PPE (gloves, goggles) to prevent irritation.
4. Case Studies
Case 1: Enhancing PCR Efficiency
A biotech firm achieved 30% higher PCR yield by adding 7 mM spermine to reduce DNA degradation.
Case 2: Drug Formulation Stability
Pharma Company X extended siRNA shelf-life by 6 months using spermine-based stabilization.
5. Client Success Stories
Client A: Gene Therapy Startup
- Challenge: Low viral vector production efficiency.
- Solution: 5 µM spermine in HEK293 cell culture.
- Result: 2x higher titer with 90% viability.
Client B: Agrochemical Leader
- Challenge: Drought-sensitive crop yields.
- Solution: Foliar spray with 0.1% spermine.
- Result: 40% higher biomass under water stress.
6. Request a Quote
Optimize your research or production with premium-grade Spermine (CAS 71-44-3). Contact us for pricing, bulk discounts, and technical support:
- Email: info@vivalr.com
- Tel: (86) 15866781826



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