4-Nitro-3-trifluoromethyl aniline CAS 393-11-3
Appearance:Yellow crystalline power
Melting point:125-128℃
Packing: 25kg/drum as customer`s requirement
Sample:available
related documents:
COA of 4-Nitro-3-trifluoromethyl Aniline
TDS of 4-Nitro-3-trifluoromethyl Aniline
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4-Nitro-3-trifluoromethyl Aniline (CAS 393-11-3) Technical Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Industrial Applications & Functional Mechanisms
- Operational Guidelines & Safety Protocols
- Synthesis Case Study: Pharmaceutical Intermediate Production
- Customer Success Stories
- Procurement Consultation & Technical Support
Product Specifications & Comparative Analysis
| Parameter | 4-Nitro-3-trifluoromethyl Aniline | Conventional Nitroanilines |
|---|---|---|
| CAS Number | 393-11-3 | Varies |
| Molecular Formula | C7H5F3N2O2 | C6H6N2O2 |
| Molecular Weight | 220.12 g/mol | 138.12 g/mol |
| Melting Point | 78-82°C | 145-148°C |
| Fluorine Content | 26.7% | 0% |
Industrial Applications & Functional Mechanisms
This specialty aromatic amine serves as critical building block in:
- Agrochemical Synthesis: Key intermediate for fluorinated herbicides/pesticides
- Pharmaceutical Development: Precursor for antitumor agents and CNS drugs
- Dye Manufacturing: Chromophore component for specialty pigments
- Polymer Chemistry: Monomer for fluorinated epoxy resins
Operational Guidelines & Safety Protocols
| Handling Requirement | Specification |
|---|---|
| Storage Conditions | 2-8°C in amber glass under nitrogen |
| Reactivity Profile | Incompatible with strong oxidizers, acids |
| PPE Requirements | Chemical goggles, neoprene gloves, Type B suits |
Synthesis Case Study: Pharmaceutical Intermediate Production
Client: European API Manufacturer (Confidential)
- Application: Synthesis of fluorinated kinase inhibitors
- Process: Buchwald-Hartwig amination coupling
- Yield Improvement: 22% increase vs. non-fluorinated analogs
- Purity Achieved: 99.8% (HPLC)
Customer Success Stories
Case 1: Agrochemical Formulator (Germany)
- Challenge: Developing persistent herbicide with reduced toxicity
- Solution: Incorporated 393-11-3 in trifluralin analogs
- Result: 40% lower aquatic toxicity vs. market benchmarks
Case 2: Electronic Materials Supplier (Japan)
- Application: Fluorinated polyimide precursors
- Dielectric Constant: Achieved 2.3 at 1 GHz
- Thermal Stability: 380°C decomposition temperature
Procurement Consultation & Technical Support
Contact our technical team for:
- Custom synthesis scale-up services
- Regulatory documentation support (REACH, TSCA)
- Application-specific formulation guidance
Email: info@vivalr.com
Tel: (86) 15866781826
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