Comprehensive Guide to 3-Chlorobenzoyl Chloride (CAS 618-46-2)
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison With Isomers
- 4. Operational Guidelines & Safety Protocols
- 5. Industry Case Studies
- 6. Technical Inquiry & Procurement Support
1. Product Overview & Specifications
Chemical Name: 3-Chlorobenzoyl Chloride
CAS No.: 618-46-2
Molecular Formula: C7H4Cl2O
Molecular Weight: 175.01 g/mol
| Property | Value |
|---|---|
| Boiling Point | 223-225°C |
| Density | 1.36 g/mL |
| Refractive Index | 1.568-1.570 |
| Flash Point | 110°C |
| Purity Grade | ≥99% (Industrial Grade) |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate
Essential for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs) and anesthetic agents. Enables precise introduction of meta-chlorobenzoyl groups in active pharmaceutical ingredients (APIs).
Agrochemical Production
Critical component in manufacturing chlorophenoxy herbicides, particularly for crop protection formulations requiring selective weed control.
Chemical Synthesis
Used as acylating agent in:
– Dye manufacturing
– Polymer modification
– Specialty chemical synthesis
3. Performance Comparison With Isomers
| Parameter | 3-Chloro Isomer | 2-Chloro Isomer | 4-Chloro Isomer |
|---|---|---|---|
| CAS No. | 618-46-2 | 609-65-4 | 122-01-0 |
| Boiling Point | 223-225°C | 238°C | 222°C |
| Reactivity | Moderate | High | Low |
| Pharma Preference | ★★★★☆ | ★★☆☆☆ | ★★★☆☆ |
4. Operational Guidelines & Safety Protocols
Handling Requirements
– Use corrosion-resistant equipment (glass/PTFE-lined reactors)
– Maintain inert atmosphere (N2 blanketing)
– Temperature control: 15-30°C range
Storage Conditions
– Hermetically sealed containers
– Ambient temperature storage
– Shelf life: 24 months from production
Safety Measures
– PPE: Acid-resistant gloves, face shield
– Emergency protocols for hydrolysis reactions
– Spill management: Neutralize with dry soda ash
5. Industry Case Studies
Case 1: Pharmaceutical API Manufacturer
Client: Leading European Pharma Company
Application: Ketamine hydrochloride synthesis
Result: 18% yield improvement vs traditional methods
Case 2: Agrochemical Formulator
Client: Asian Crop Protection Specialist
Application: Chlorophenoxy herbicide production
Result: 99.2% purity achieved in final product
Case 3: Specialty Chemical Producer
Client: US-based Polymer Company
Application: Flame retardant additive synthesis
Result: 40% reduction in side reactions
6. Technical Inquiry & Procurement Support
Our chemical engineering team provides:
– Custom synthesis protocols
– Regulatory compliance documentation
– Just-in-time delivery solutions
Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
Why Choose Us:
– ISO-certified production facilities
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