3-Chlorobenzoyl Chloride CAS 618-46-2

Synonyms: Meta Chloro Benzoyl Chloride
Purity: 99%min
Appearance: Clear colorless liquid
Packing: 200kg/drum
Sample: Available

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Comprehensive Guide to 3-Chlorobenzoyl Chloride (CAS 618-46-2)

Table of Contents

1. Product Overview & Specifications

Chemical Name: 3-Chlorobenzoyl Chloride
CAS No.: 618-46-2
Molecular Formula: C7H4Cl2O
Molecular Weight: 175.01 g/mol

Property Value
Boiling Point 223-225°C
Density 1.36 g/mL
Refractive Index 1.568-1.570
Flash Point 110°C
Purity Grade ≥99% (Industrial Grade)

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Essential for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs) and anesthetic agents. Enables precise introduction of meta-chlorobenzoyl groups in active pharmaceutical ingredients (APIs).

Agrochemical Production

Critical component in manufacturing chlorophenoxy herbicides, particularly for crop protection formulations requiring selective weed control.

Chemical Synthesis

Used as acylating agent in:
– Dye manufacturing
– Polymer modification
– Specialty chemical synthesis

3. Performance Comparison With Isomers

Parameter 3-Chloro Isomer 2-Chloro Isomer 4-Chloro Isomer
CAS No. 618-46-2 609-65-4 122-01-0
Boiling Point 223-225°C 238°C 222°C
Reactivity Moderate High Low
Pharma Preference ★★★★☆ ★★☆☆☆ ★★★☆☆

4. Operational Guidelines & Safety Protocols

Handling Requirements

– Use corrosion-resistant equipment (glass/PTFE-lined reactors)
– Maintain inert atmosphere (N2 blanketing)
– Temperature control: 15-30°C range

Storage Conditions

– Hermetically sealed containers
– Ambient temperature storage
– Shelf life: 24 months from production

Safety Measures

– PPE: Acid-resistant gloves, face shield
– Emergency protocols for hydrolysis reactions
– Spill management: Neutralize with dry soda ash

5. Industry Case Studies

Case 1: Pharmaceutical API Manufacturer

Client: Leading European Pharma Company
Application: Ketamine hydrochloride synthesis
Result: 18% yield improvement vs traditional methods

Case 2: Agrochemical Formulator

Client: Asian Crop Protection Specialist
Application: Chlorophenoxy herbicide production
Result: 99.2% purity achieved in final product

Case 3: Specialty Chemical Producer

Client: US-based Polymer Company
Application: Flame retardant additive synthesis
Result: 40% reduction in side reactions

6. Technical Inquiry & Procurement Support

Our chemical engineering team provides:
– Custom synthesis protocols
– Regulatory compliance documentation
– Just-in-time delivery solutions

Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us:
– ISO-certified production facilities
– Batch-to-batch consistency guarantee
– Global logistics network

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