N-Decyl-α-D-maltopyranoside, Anagrade CAS 168037-12-5: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
N-Decyl-α-D-maltopyranoside (CAS 168037-12-5) is a high-purity, non-ionic detergent widely used in membrane protein solubilization and stabilization. Key parameters include:
| Parameter | N-Decyl-α-D-maltopyranoside | Competitor A (Deoxycholate) | Competitor B (DDM) |
|---|---|---|---|
| CMC (mM) | 1.6 | 4-6 | 0.17 |
| Molecular Weight | 510.5 g/mol | 432.6 g/mol | 510.7 g/mol |
| Purity | ≥98% (HPLC) | ≥95% |
2. Applications & Use Cases
2.1 Membrane Protein Research
Ideal for solubilizing GPCRs, ion channels, and transporters while maintaining native conformation.
2.2 Virology Applications
Used in viral envelope protein extraction for vaccine development (e.g., influenza HA proteins).
2.3 Diagnostic Reagents
Employed in lateral flow assays to stabilize conjugated antibodies without affecting binding affinity.
3. Step-by-Step Usage Guidelines
3.1 Preparation
1. Prepare 10% (w/v) stock solution in ultrapure water
2. Filter through 0.22 μm membrane
3. Store at -20°C in aliquots
3.2 Concentration Optimization
Typical working concentrations:
– Membrane solubilization: 1-2×CMC
– Protein stabilization: 0.5-1×CMC
4. Real-World Case Studies
4.1 Biotech Company X: GPCR Structural Study
Challenge: Low yield of active β2-adrenergic receptor
Solution: 1.8% N-Decyl-α-D-maltopyranoside in purification buffer
Result: 3× improved receptor stability for cryo-EM analysis
4.2 Pharma Company Y: Vaccine Development
Challenge: RSV fusion protein degradation
Solution: 0.05% detergent in formulation buffer
Result: 6-month stability at 4°C achieved
5. Technical Support & Inquiry
For batch-specific data or custom formulations:
Email: info@vivalr.com
Tel: (86) 15866781826
Why Choose Our Product?
- Batch-to-batch consistency (HPLC verified)
- Low endotoxin levels (<0.1 EU/mg)
- Custom concentration packaging available
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