Ethyl Methanesulfonate (CAS 62-50-0): Comprehensive Technical Guide
Table of Contents
1. Basic Information & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 62-50-0 |
| Molecular Formula | C3H8O3S |
| Molecular Weight | 124.16 g/mol |
| Appearance | Colorless liquid |
| Density | 1.20–1.21 g/cm³ |
| Boiling Point | 85–86°C (10 mmHg) |
| Flash Point | 100°C |
| Solubility | Miscible with ethanol; slightly soluble in water |
2. Key Applications
Molecular Biology & Genetics
- DNA Alkylating Agent: Induces point mutations by ethylating guanine at the O6 position, leading to G/C→A/T base substitutions.
- Mutagenesis Studies: Widely used to create random mutations in model organisms (e.g., Arabidopsis, rice, wheat) for functional genomics research.
- Cancer Research: Serves as a reference carcinogen to study DNA repair mechanisms and chemical carcinogenesis.
3. Safety & Handling
Hazard Information
- Health Risks: Confirmed mutagen and suspected carcinogen (Category 1B). May cause skin/eye irritation and respiratory distress.
- Storage: Store in sealed containers at room temperature, away from moisture, alkalies, and oxidizing agents.
- Handling: Use PPE (gloves, goggles, lab coat) and work in a fume hood. Avoid inhalation or direct contact.
4. Product Specifications & Suppliers
| Supplier | Purity | Packaging | Price (USD) |
|---|---|---|---|
| Leyan.com | ≥98% | 5g, 10g, custom | $5–$10/g |
| Shanghai Guchen Biotech | 99% | 5g–500g | $36–$12/g |
| Huanyu Tech | Research Grade | 5g–bulk | Contact for quote |
Request a Quote or Technical Support
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