Diisopropyl Azodicarboxylate (CAS 2446-83-5) Ultimate User Guide
Contents
- Product Specifications & Comparative Analysis
- Comprehensive Applications
- Operational Guidelines
- Industry Application Cases
- Client Success Stories
- Expert Consultation
Product Specifications & Comparative Analysis
| Parameter | Diisopropyl Azodicarboxylate | Diethyl Azodicarboxylate |
|---|---|---|
| CAS Number | 2446-83-5 | 1972-28-7 |
| Molecular Formula | C8H14N2O4 | C6H10N2O4 |
| Purity Grade | 98%-99.5% (Pharma Grade Available) | 95%-98% |
| Storage Temperature | 2-8°C (Long-term) | Ambient (Short-term) |
Comprehensive Applications
Core Functional Applications
- Mitsunobu Reaction: Essential reagent for stereospecific C-O bond formation
- Polymer Chemistry: Radical initiator in controlled polymerization
- Pharmaceutical Intermediates: Key component in nucleoside analog synthesis
Operational Guidelines
Recommended Reaction Conditions
| Application | Solvent | Temperature | Molar Ratio |
|---|---|---|---|
| Mitsunobu Reaction | THF/DMF | 0-25°C | 1:1.2 (Substrate:Reagent) |
Industry Application Cases
Case 1: Antiviral Drug Synthesis
Used in continuous flow chemistry system for Remdesivir intermediate production (Batch yield improvement: 22%)
Client Success Stories
PharmaTech Solutions (Germany)
- Challenge: Low conversion rate in steroid derivatization
- Solution: Optimized DIAD/TPP ratio (1:1.5)
- Result: 92% yield achieved (from 68%)
Expert Consultation
Contact our chemical engineers for application support:
Email: info@vivalr.com
Tel: (86) 15866781826
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