Table of Contents
- Product Overview & Specifications
- Key Applications of Bromopyruvic Acid
- Laboratory & Industrial Usage Guidelines
- Client Case Studies (2020-2024)
- Technical & Purchasing Support
Bromopyruvic Acid (CAS 1113-59-3): Product Overview
Chemical Specifications
| Parameter | Bromopyruvic Acid | Chloropyruvic Acid | Iodopyruvic Acid |
|---|---|---|---|
| CAS Number | 1113-59-3 | 522-21-8 | 3714-30-3 |
| Molecular Formula | C3H3BrO3 | C3H3ClO3 | C3H3IO3 |
| Molecular Weight | 167.96 g/mol | 122.5 g/mol | 213.96 g/mol |
| Purity | >98% (HPLC) | >95% | >97% |
| Storage | 2-8°C (desiccated) | Ambient | 2-8°C |
Physicochemical Properties
- Appearance: White to pale yellow crystalline powder
- Solubility: Soluble in DMSO, methanol; limited in water
- Melting Point: 118-122°C
- pH Stability: 4.0-7.5 (aqueous solutions)
Industrial & Research Applications
Pharmaceutical Development
Used as key intermediate in:
- Anticancer drug candidates targeting glycolytic pathways
- Enzyme inhibitors for metabolic disease research
- Cross-linking agent in protein modification
Biochemical Research
- Inhibition studies of pyruvate kinases (IC50: 15-30 μM)
- Apoptosis induction in tumor cell lines (tested on HepG2, MCF-7)
- Metabolic flux analysis in 13C-NMR studies
Agricultural Chemistry
- Precursor for herbicide intermediates
- Antimicrobial formulations for crop protection
Operational Protocols
Laboratory Handling
| Application | Concentration | Reaction Time | Yield |
|---|---|---|---|
| Cell Culture Studies | 0.1-2 mM | 24-72 hrs | N/A |
| Enzyme Assays | 5-50 μM | 30-120 min | 85-92% |
| Chemical Synthesis | 0.5-2 M | 4-12 hrs | 70-88% |
Industrial Scale Processing
- GMP-compliant batches available (500kg+ quantities)
- Customizable particle size: 50-200 μm
- Stability data: 36 months when stored properly
Documented Client Implementations
Case 1: OncoResearch Labs (2022)
- Application: Development of hepatocellular carcinoma treatment
- Usage: 15kg over 18-month research period
- Outcome: 40% tumor growth inhibition in preclinical models
Case 2: AgriGrowth Solutions (2023)
- Application: Novel fungicide formulation
- Usage: 320kg pilot production
- Outcome: 92% efficacy against Botrytis cinerea
Case 3: BioPharm Innovations (2024)
- Application: ADC (Antibody-Drug Conjugate) linker development
- Usage: 45kg for process optimization
- Outcome: Successful IND submission with improved payload release
Technical & Commercial Support
Available services:
- Sample requests (100g minimum)
- Regulatory documentation support (CoA, MSDS, DMF)
- Custom synthesis projects (purity up to 99.5%)
Contact manufacturing specialists:
Email: info@vivalr.com
Tel: (86) 15866781826



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