hbtu cas 94790-37-1

HBTU (CAS 94790-37-1) Comprehensive User Guide

Table of Contents

• 1. Product Overview & Technical Specifications
• 2. Key Applications & Industry Uses
• 3. Operational Guidelines & Best Practices
• 4. Comparative Analysis With Alternative Reagents
• 5. Verified Customer Success Stories
• 6. Technical Support & Procurement Assistance

1. Product Overview & Technical Specifications

HBTU (O-Benzotriazole-N,N,N’,N’-tetramethyluronium hexafluorophosphate, CAS 94790-37-1) is a superior peptide coupling reagent widely adopted in solid-phase synthesis.

2. Key Applications & Industry Uses

Primary applications include:

• Solid-phase peptide synthesis activation
• Carbodiimide-free amide bond formation
• Pharmaceutical intermediate preparation
• Complex molecule conjugation in drug discovery

3. Operational Guidelines & Best Practices

Step-by-Step Protocol:

1. Prepare 0.5M solution in anhydrous DMF/DCM
2. Maintain molar ratio 1:1:2 (Acid:HBTU:Base)
3. React at 0-5°C under nitrogen atmosphere
4. Monitor reaction progress via TLC/LCMS

4. Comparative Analysis With Alternative Reagents

5. Verified Customer Success Stories

Case Study 1: Leading Shanghai Pharma Company

• Challenge: Low yield (38%) in cyclic peptide synthesis
• Solution: Implemented HBTU-based coupling system
• Outcome: Achieved 82% yield with 99.2% purity

Case Study 2: Beijing University Research Team

• Application: Dendrimer functionalization
• Process: 15-step conjugation protocol
• Result: Reduced reaction time by 40% vs DCC method

6. Technical Support & Procurement Assistance

Our experts provide:

• Bulk pricing (1kg+ quantities)
• Custom synthesis services
• GMP-grade manufacturing options

Contact our technical team:
Email: info@vivalr.com
Phone: (86) 15866781826

Request Custom Quote: Specify required quantity, purity grade, and application details for expedited service.