Mafenide Hydrochloride (CAS 138-37-4): Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Usage
- 3. Clinical Case Studies
- 4. Industry Adoption & Customer Success Stories
- 5. Procurement Guidance & Contact
1. Product Overview & Specifications
| Parameter | Mafenide Hydrochloride | Alternative (Silver Sulfadiazine) |
|---|---|---|
| CAS Number | 138-37-4 | 22199-08-2 |
| Molecular Formula | C7H10ClN2O2S | C10H9AgN4O2S |
| Appearance | White crystalline powder | White to cream-colored paste |
| Solubility | Water-soluble (5% solution) | Water-insoluble |
| Antimicrobial Spectrum | Broad-spectrum vs Gram+/Gram- | Limited Pseudomonas coverage |
2. Key Applications & Usage
Primary Medical Uses
- Burn wound infection prevention (2nd/3rd degree)
- Treatment of infected thermal injuries
- Post-debridement wound management
Mechanism of Action
Competitively inhibits bacterial para-aminobenzoic acid (PABA) utilization, disrupting folic acid synthesis. Demonstrates superior tissue penetration compared to other sulfonamides.
3. Clinical Case Studies
Case 1: Severe Electrical Burns
Patient: 32M with 40% TBSA electrical burns
Protocol: 5% mafenide solution applied bid post-escharotomy
Outcome: Wound colonization reduced by 78% at Day 7
Case 2: Combat-Related Trauma
Scenario: Field treatment of blast injuries in tropical environment
Result: 92% infection-free rate vs 67% with standard SSD
4. Industry Adoption & Customer Success Stories
Regional Burn Center (Miami, FL)
| Challenge | Solution | Outcome (12-month data) |
|---|---|---|
| Persistent Pseudomonas infections | Switched to mafenide protocol | ↓ 41% antibiotic-resistant cases |
Military Medical Unit (San Antonio, TX)
| Application | Implementation | Efficacy |
|---|---|---|
| Mass casualty triage | Pre-moistened 5% dressings | 87% faster wound stabilization |
5. Procurement Guidance & Contact
Certifications: US FDA 510(k) Cleared, WHO Essential Medicine
Packaging: 25kg drums (GMP-grade), clinical 50g tubes
Lead Time: 2-4 weeks (bulk orders)
Contact our pharmaceutical specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
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