4′-chloroacetophenone cas 99-91-2

4′-Chloroacetophenone (CAS 99-91-2) Ultimate User Guide: Applications, Case Studies & Procurement Insights

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industry Uses
• 3. Technical Parameter Comparison
• 4. Operational Best Practices
• 5. Verified Customer Case Studies
• 6. Sourcing & Customization Solutions

1. Product Overview & Specifications

4′-Chloroacetophenone (CAS 99-91-2) is an aromatic ketone derivative with molecular formula C₈H₇ClO. This white crystalline solid serves as critical building block in organic synthesis.

2. Key Applications & Industry Uses

Pharmaceutical Intermediate

Critical precursor for antihistamines, antipsychotics, and COX-2 inhibitors. Enables efficient synthesis of chlorpheniramine maleate.

Agrochemical Production

Used in manufacturing chlorinated pesticide intermediates and fungicide precursors.

Photopolymerization

Essential component in UV-curable coatings and photoinitiator systems (e.g., Darocur® formulations).

3. Technical Parameter Comparison

4. Operational Best Practices

Handling Protocols

• Use NIOSH-approved respirators when handling powder
• Maintain inert atmosphere during high-temperature reactions

Reaction Optimization

• Friedel-Crafts acetylation: 0.8-1.2 molar ratio
• Grignard reactions: -10°C to 25°C range

5. Verified Customer Case Studies

Case 1: Pharmaceutical Manufacturer (Germany)

• Challenge: Scale-up of antihistamine API batch production
• Solution: Optimized Cl-acetophenone purification (99.7% purity)
• Outcome: 22% yield improvement, reduced catalyst loading

Case 2: Agrochemical Formulator (India)

• Application: Chlorinated fungicide intermediate
• Result: Achieved 98.5% conversion rate at 80°C
• Volume: 15 metric tons/month continuous supply

6. Sourcing & Customization Solutions

Our GMP-certified facility provides:

• Bulk quantities (25kg drums to metric ton containers)
• Custom purity grades (98%-99.99%)
• Tailored packaging (nitrogen-flushed bags, stainless steel kegs)

Contact Technical Experts:
Email: info@vivalr.com
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Request SDS, COA, or custom synthesis proposals within 24 hours.