4-dimethylaminobenzaldehyde cas 100-10-7

Chemical Name: 4-Dimethylaminobenzaldehyde
CAS No.: 100-10-7
Molecular Formula:C9H11NO
Molecular weight: 149.19
Appearance:Light blue to white powder or crystal
Assay: 99%

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4-Dimethylaminobenzaldehyde (CAS 100-10-7) Buyer’s Guide & Industry Insights

Table of Contents

1. Product Overview & Specifications

Parameter Specification Test Method
CAS Number 100-10-7 N/A
Molecular Formula C9H11NO Elemental Analysis
Purity ≥99% (HPLC) USP 621
Melting Point 72-75°C DSC
Storage 2-8°C in amber glass ICH Q7

2. Key Applications & Industrial Uses

Core Functional Roles:

  • Pharmaceutical Intermediate: Critical in synthesis of antimalarial drugs (e.g., Chloroquine derivatives) and antihistamines
  • Analytical Chemistry: Ehrlich’s reagent component for indole detection in microbiology
  • Dye Manufacturing: Precursor for triphenylmethane dyes
  • Organic Synthesis: Aldehyde group participates in condensation reactions

3. Technical Comparison: Grade Variations

Grade Pharmaceutical Industrial Research
Purity 99.5%+ 98% 95%
Heavy Metals <10ppm <50ppm N/A
Certification GMP, DMF ISO 9001 N/A

4. Operational Guidelines & Safety Protocols

Best Practices:

  • Handling: Use nitrile gloves and chemical goggles (EN 166 compliance)
  • Storage: Nitrogen atmosphere for long-term preservation
  • Incompatibilities: Avoid strong oxidizers & amines
  • Waste Management: Neutralize with dilute acetic acid before disposal

5. Case Studies: Pharmaceutical Intermediate Synthesis

Case 1: Antimalarial Drug Production

Process Flow:
Condensation with ethyl acetoacetate → Cyclization → Purification (HPLC) → Final API

Yield Optimization: Achieved 82% yield at 60°C with 2:1 molar ratio

6. Client Success Stories

Client A: European Pharma Manufacturer

  • Challenge: Required GMP-grade material with <0.1% impurity profile
  • Solution: Custom synthesis with 3-step purification
  • Outcome: 30% cost reduction vs. previous supplier

Client B: US Research Institute

  • Project: Development of novel indole detection method
  • Technical Support: Provided optimized reagent formulations
  • Result: 50% faster reaction time achieved

7. Request Customized Quotation

Contact our technical team for batch-specific COAs and regulatory support:

Customization Options:

  • Bulk quantities (25kg drums)
  • Special packaging (vacuum-sealed aliquots)
  • Regulatory documentation packages
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