4-Dimethylaminobenzaldehyde (CAS 100-10-7) Buyer’s Guide & Industry Insights
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Technical Comparison: Grade Variations
- 4. Operational Guidelines & Safety Protocols
- 5. Case Studies: Pharmaceutical Intermediate Synthesis
- 6. Client Success Stories
- 7. Request Customized Quotation
1. Product Overview & Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| CAS Number | 100-10-7 | N/A |
| Molecular Formula | C9H11NO | Elemental Analysis |
| Purity | ≥99% (HPLC) | USP 621 |
| Melting Point | 72-75°C | DSC |
| Storage | 2-8°C in amber glass | ICH Q7 |
2. Key Applications & Industrial Uses
Core Functional Roles:
- Pharmaceutical Intermediate: Critical in synthesis of antimalarial drugs (e.g., Chloroquine derivatives) and antihistamines
- Analytical Chemistry: Ehrlich’s reagent component for indole detection in microbiology
- Dye Manufacturing: Precursor for triphenylmethane dyes
- Organic Synthesis: Aldehyde group participates in condensation reactions
3. Technical Comparison: Grade Variations
| Grade | Pharmaceutical | Industrial | Research |
|---|---|---|---|
| Purity | 99.5%+ | 98% | 95% |
| Heavy Metals | <10ppm | <50ppm | N/A |
| Certification | GMP, DMF | ISO 9001 | N/A |
4. Operational Guidelines & Safety Protocols
Best Practices:
- Handling: Use nitrile gloves and chemical goggles (EN 166 compliance)
- Storage: Nitrogen atmosphere for long-term preservation
- Incompatibilities: Avoid strong oxidizers & amines
- Waste Management: Neutralize with dilute acetic acid before disposal
5. Case Studies: Pharmaceutical Intermediate Synthesis
Case 1: Antimalarial Drug Production
Process Flow:
Condensation with ethyl acetoacetate → Cyclization → Purification (HPLC) → Final API
Yield Optimization: Achieved 82% yield at 60°C with 2:1 molar ratio
6. Client Success Stories
Client A: European Pharma Manufacturer
- Challenge: Required GMP-grade material with <0.1% impurity profile
- Solution: Custom synthesis with 3-step purification
- Outcome: 30% cost reduction vs. previous supplier
Client B: US Research Institute
- Project: Development of novel indole detection method
- Technical Support: Provided optimized reagent formulations
- Result: 50% faster reaction time achieved
7. Request Customized Quotation
Contact our technical team for batch-specific COAs and regulatory support:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Customization Options:
- Bulk quantities (25kg drums)
- Special packaging (vacuum-sealed aliquots)
- Regulatory documentation packages



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