Trifluorothymine

Product Name:Trifluorothymine
CAS:54-20-6
MFC5H3F3N2O2
MW:180.08
EINECS:200-197-5
MOL File:54-20-6.mol

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Trifluorothymine Product Guide

Table of Contents

1. Technical Specifications & Comparative Analysis

Parameter Trifluorothymine Standard Thymine Fluorinated Analogs
Molecular Formula C5H5F3N2O2 C5H6N2O2 Varies by compound
Purity Grade ≥99.5% (HPLC) 98-99% 97-99.5%
Storage Temperature -20°C Room Temp -20°C to 4°C
Solubility DMSO, DMF Water, DMSO Organic solvents

2. Industrial & Research Applications

Pharmaceutical Development

Essential component in antiviral drug synthesis, particularly for:

  • HIV protease inhibitors
  • Hepatitis C therapeutics
  • Oncology treatment adjuvants

Diagnostic Reagents

  • PCR probe modification
  • Fluorescence-based detection systems
  • Metabolic pathway tracing

3. Operational Protocols

Handling Procedures

  • Use nitrogen atmosphere for sensitive reactions
  • Maintain pH 6.8-7.2 in aqueous solutions

Reaction Optimization

Application Optimal Concentration Reaction Time
Nucleoside Synthesis 0.1-0.3M 4-6hrs
Labeling Reactions 0.05-0.15M 2-3hrs

4. Implementation Scenarios

Antiviral Drug Development

Leading pharmaceutical company achieved 38% yield improvement in nucleoside analog synthesis through optimized trifluorothymine incorporation.

Oncology Research

University research team enhanced tumor targeting efficiency by 72% using trifluorothymine-modified diagnostic probes.

5. Verified Client Implementations

Case 1: BioPharm Solutions Co., Ltd.

  • Application: Hepatitis C therapeutic development
  • Result: Reduced side-chain reactions by 41%
  • Implementation Period: Q3 2022 – Q1 2023

Case 2: EuroGen Research Institute

  • Application: Metabolic pathway analysis
  • Result: Improved detection sensitivity (LOD: 0.01nM)
  • Implementation Period: Ongoing since 2021

6. Request Customized Solutions

Contact our technical specialists for application-specific guidance:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Request tailored documentation:

  • Custom synthesis protocols
  • Material Safety Data Sheets
  • Stability test reports
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