2-Amino-4-chloro-6-methylpyrimidine

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2-Amino-4-chloro-6-methylpyrimidine: Technical Guide & Application Insights

1. Product Overview & Specifications

Basic Parameters

Parameter Specification
CAS Number 5600-27-7
Molecular Formula C5H6ClN3
Molecular Weight 143.57 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder

Comparative Analysis

Grade Industrial Pharmaceutical Research
Purity 95-97% ≥99% ≥98%
Residual Solvents <0.5% <0.1% <0.3%

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesis of kinase inhibitors and antiviral agents. Demonstrates exceptional reactivity in nucleophilic substitution reactions.

Agrochemical Development

Critical component in fungicide formulations, particularly effective against Botrytis cinerea in crop protection.

Material Science

Enables creation of coordination polymers with thermal stability up to 300°C for specialty coatings.

3. Usage Scenarios & Best Practices

Industrial Synthesis

Typical Reaction: 0.1mol compound + 1.2eq alkylating agent in DMF at 60°C under N2 achieves 82-88% yield.

Lab-scale Purification

Recrystallization recommendation: Ethanol/water (3:1 v/v) with 5°C/min cooling gradient.

4. Verified Customer Case Studies

Case 1: Novo Pharmaceuticals (2023)

Challenge: Scale-up of antiviral intermediate from 10g to 50kg batch
Solution: Optimized catalytic system using our 99.5% grade material
Result: 22% yield improvement vs. competitor products

Case 2: AgroGreen Solutions (2024)

Challenge: Fungicide resistance in vineyard applications
Solution: Formulation containing 15% w/w 2-Amino-4-chloro-6-methylpyrimidine
Result: 94% disease suppression vs. 78% industry benchmark

5. Inquiry & Custom Solutions

Request technical documents or discuss bulk orders:
Email: info@vivalr.com
Tel: (86) 15866781826

Our experts provide:
– Batch-specific COA documentation
– Regulatory support (REACH, FDA DMF)
– Custom particle size distributions (10-200μm)

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