2-(4-Aminophenyl)ethylamine Dihydrochloride (CAS 13078-82-5) Comprehensive Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 13078-82-5 |
| Chemical Name | 2-(4-Aminophenyl)ethylamine dihydrochloride |
| Molecular Formula | C8H13N2Cl2 |
| Molecular Weight | 219.11 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Water: 50 mg/mL, Ethanol: 30 mg/mL |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical precursor in serotonin/norepinephrine reuptake inhibitor development.
Organic Synthesis: Building block for:
- Antidepressant APIs
- Dopamine analogs
- Polymer cross-linking agents
Material Science: Surface modification agent for conductive polymers.
3. Usage Guidelines & Best Practices
Handling Protocols:
- Use nitrogen atmosphere for moisture-sensitive reactions
- Optimal pH range: 6.5-7.5 (aqueous solutions)
Reaction Optimization:
- Coupling Reactions: 0.1-0.3 molar equivalents
- Amidation: 65-75°C reaction temperature
4. Case Studies & Real-World Implementations
Case Study 1: NeuroPharm Solutions (2024)
- Application: SNRI intermediate scale-up
- Result: 22% yield improvement vs. previous synthesis route
Case Study 2: PolyTech Materials (2023)
- Application: Conductive polymer modification
- Result: Achieved 15% higher conductivity
5. Technical Comparison with Alternatives
| Parameter | CAS 13078-82-5 | Similar Compound A |
|---|---|---|
| Thermal Stability | Stable to 150°C | Decomposes at 110°C |
| Aqueous Solubility | 50 mg/mL | 28 mg/mL |
| Catalytic Efficiency | 92% yield | 78% yield |
6. Inquiry & Professional Consultation
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (100kg+ quantities)
- Regulatory documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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