Ethyl (R)-(-)-4-cyano-3-hydroxybutyate CAS 141942-85-0

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate (CAS 141942-85-0) Ultimate Guide

Table of Contents

• Product Specifications & Comparative Analysis
• Key Applications & Industrial Uses
• Operational Best Practices
• Industry Application Scenarios
• Verified Client Success Stories
• Expert Consultation & Quotation

1. Technical Specifications & Competitive Benchmarking

2. Pharmaceutical & Chemical Applications

Primary Functions:

• Key chiral intermediate for statin drugs (Atorvastatin/Rosuvastatin)
• Building block for β-hydroxy nitrile derivatives
• Precursor in asymmetric synthesis of γ-amino alcohols

Industry Utilization:

• Cholesterol-lowering medication production
• Enantioselective catalysis processes
• Advanced material synthesis

3. Operational Protocols

Handling Requirements:

• Storage: 2-8°C under inert atmosphere
• Solvent Compatibility: Ethanol, DCM, THF
• Reaction Conditions: 0-5°C for stereochemical integrity

4. Implementation Scenarios

Scenario 1: Continuous flow synthesis of Rosuvastatin calcium

Scenario 2: Multi-kilogram scale enantiomeric resolution

5. Client Implementation Cases

Case Study 1: Top-10 Pharma Company (2022)

• Challenge: Scaling from lab to 500kg production
• Solution: Optimized crystallization protocol
• Outcome: 92% yield improvement

Case Study 2: EU Research Consortium (2023)

• Challenge: Maintaining ee >99% in API synthesis
• Solution: Custom purity grade development
• Outcome: Successful Phase III trial material

6. Technical Support & Commercial Inquiry

Contact our chemistry experts for:

• Bulk pricing (100kg+ quantities)
• Custom synthesis protocols
• Regulatory documentation support

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