Fmoc-lys(dde)-Oh Cas 150629-67-7

Comprehensive Guide to Fmoc-Lys(Dde)-OH (CAS 150629-67-7)

Table of Contents

• Product Overview & Specifications
• Key Applications
• Usage Case Studies
• Client Success Stories
• Contact for Custom Solutions

1. Product Overview & Specifications

2. Key Applications in Peptide Synthesis

Orthogonal Protection Strategy: Enables selective deprotection of lysine side chains during SPPS (Solid-Phase Peptide Synthesis). The Dde group is removed by 2% hydrazine in DMF, while Fmoc is cleaved under basic conditions.

Complex Peptide Architectures: Critical for synthesizing branched peptides, cyclic peptides, and dendrimers requiring multiple orthogonal protections.

3. Usage Case Studies

Case 1: Synthesis of HIV-1 Protease Inhibitor Precursor

Used Fmoc-Lys(Dde)-OH to protect lysine residues during synthesis of a 32-mer peptide. Dde removal achieved 98% efficiency without affecting Fmoc groups.

Case 2: Fluorescent Labeling in Cancer Targeting Peptides

Enabled site-specific conjugation of FITC dye to lysine side chains after selective Dde deprotection in VEGF inhibitor peptides.

4. Verified Client Implementations

5. Technical Consultation & Ordering

Request custom synthesis protocols or bulk pricing for your peptide project:

• Email: info@vivalr.com
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