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Sulfamethazine (CAS 57-68-1): Comprehensive Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 57-68-1 |
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.33 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Melting Point | 197–200°C |
| Water Solubility | 150 mg/100 mL (29°C) |
| Storage Conditions | 2–8°C, protected from light |
2. Key Applications
Sulfamethazine is a sulfonamide antibiotic widely used in:
- Veterinary Medicine: Treatment of bacterial infections in livestock (e.g., avian cholera, swine dysentery).
- Antimicrobial Research: Inhibition of Gram-positive and Gram-negative bacteria.
- Metabolism Studies: Investigation of cytochrome P450 (CYP3A4) induction and N-acetyltransferase activity.
3. Usage Guidelines
Recommended Dosages
- Poultry: 0.1–0.2% in feed for 5–7 days.
- Swine: 25–50 mg/kg body weight daily.
Precautions
- Avoid prolonged exposure to light or moisture.
- Incompatible with strong oxidizing agents.
4. Safety & Handling
| Hazard Class | GHS Pictogram | Precautionary Measures |
|---|---|---|
| Reproductive Toxicity (Category 2) |  |
|
5. Supplier Case Studies
Case 1: Shanghai Taosu Biotechnology
- Application: Supplied 99.73% pure Sulfamethazine for pharmacokinetic research.
- Outcome: Enabled gender-dependent metabolism studies in rodent models.
Case 2: Hubei Topfond Chemical Co.
- Application: Bulk supply for veterinary formulations.
- Outcome: Achieved 98% efficacy in treating bovine respiratory infections.
6. Contact for Quotation
For pricing, COA, or bulk orders:
- Email: info@vivalr.com
- Tel: (86) 15866781826
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