N-Boc-3-pyrrolidinone

Product Name:N-Boc-3-pyrrolidinone
CAS:101385-93-7
MFC9H15NO3
MW:185.22
EINECS:600-204-5
MOL File:101385-93-7.mol

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N-Boc-3-pyrrolidinone: Comprehensive Product Guide & Industry Applications

1. Product Overview & Key Specifications

Parameter Specification Competitor A Competitor B
CAS Number 101385-93-7 Same Same
Purity ≥98% (HPLC) ≥95% ≥97%
Molecular Formula C9H15NO3 Same Same
Storage Temp 2-8°C Room Temp 2-8°C
Packaging 1kg, 5kg, 25kg 100g, 1kg 500g, 5kg

2. Applications in Pharmaceutical & Chemical Synthesis

Key Application Areas:

  • Intermediate in β-amino acid derivatives synthesis
  • Building block for kinase inhibitors (e.g., JAK2 inhibitors)
  • Peptidomimetics development
  • Chiral catalyst preparation

3. Usage Guidelines & Best Practices

Typ Reaction Conditions:

  • Boc Deprotection: TFA/DCM (1:4), 0°C to RT, 2-4hrs
  • Storage: Argon atmosphere recommended for long-term storage

4. Industry Case Studies

Case 1: Omarigliptin Intermediate Synthesis

  • Reaction: N-Boc-3-pyrrolidinone → 3-aminopyrrolidine
  • Yield Improvement: 68% → 82% after process optimization

5. Client Success Stories

Client 1: Top 10 Pharma Company (EU)

Parameter Details
Application JAK1/2 Inhibitor Development
Annual Usage 85kg (2024)
Purity Requirement ≥99% (chiral HPLC)

6. Request Customized Quotation

Contact our technical team for batch-specific COA:

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