2,3,6-Trifluoropyridine: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications & Industry Uses
- 3. Usage Scenarios & Case Studies
- 4. Client Success Stories
- 5. Request a Quote or Sample
1. Product Overview & Specifications
2,3,6-Trifluoropyridine (CAS 374-70-9) is a fluorinated heterocyclic compound widely used in pharmaceuticals, agrochemicals, and specialty materials.
Key Parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C5H2F3N |
| Molecular Weight | 133.07 g/mol |
| Purity | >98% |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 112-114°C |
Comparative Analysis:
| Compound | Fluorine Positions | Reactivity | Cost Efficiency |
|---|---|---|---|
| 2,3,6-Trifluoropyridine | 2,3,6 | High | ★★★☆☆ |
| 2-Fluoropyridine | 2 | Moderate | ★★★★☆ |
| Pentafluoropyridine | All positions | Very High | ★☆☆☆☆ |
2. Applications & Industry Uses
Pharmaceutical Intermediates
Used in synthesizing antiviral drugs (e.g., HIV protease inhibitors) and kinase inhibitors due to its electron-withdrawing properties.
Agrochemical Formulations
Key component in herbicides and insecticides, enhancing compound stability and bioavailability.
Electronic Materials
Building block for liquid crystals and OLED materials, offering optimal dielectric properties.
3. Usage Scenarios & Case Studies
Case 1: Pharmaceutical Intermediate Synthesis
Objective: Synthesize Sofosbuvir intermediate
Process: 2,3,6-Trifluoropyridine reacted with ribose derivative under Pd-catalyzed coupling
Outcome: 92% yield, reduced byproducts vs. alternative fluoropyridines
Case 2: Herbicide Development
Challenge: Improve soil persistence of glyphosate analog
Solution: Introduce 2,3,6-trifluoropyridine moiety
Result: 40% longer field efficacy at 20% lower dosage
4. Client Success Stories
Client 1: ABC Pharma (USA)
Project: Kinase inhibitor for non-small cell lung cancer
Role: Critical intermediate in lead compound optimization
Metrics: Accelerated timeline by 6 months, IC50 improved from 78nM to 12nM
Client 2: AgroGreen Co. (Germany)
Application: Next-gen insecticide against resistant pests
Results: 98% pest mortality at 50ppm vs. 72% with previous formulation
Testimonial: “Vivalr’s 2,3,6-Trifluoropyridine exceeded purity specs and enabled scale-up without process changes.” – Dr. Schmidt, R&D Head
5. Request a Quote or Sample
Vivalr provides GMP-grade 2,3,6-Trifluoropyridine with:
- Batch-to-batch consistency (≥98.5% purity)
- Custom packaging (1kg to 1000kg)
- Global regulatory support (REACH, DMF filings)
Contact our technical team:
✉️ info@vivalr.com
(86) 15866781826


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