2-Bromo-4-cyanopyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Bromo-4-cyanopyridine (CAS: 10386-27-3) is a halogenated pyridine derivative with the molecular formula C6H3BrN2 and a molecular weight of 183.01 g/mol. It is widely used in pharmaceutical intermediates and organic synthesis.
| Parameter | Specification |
|---|---|
| Purity | ≥95% (TRC), ≥99% (Pharmaceutical Grade) |
| Packaging | 1g, 5g, 25g, 500g, 2.5kg (Customizable) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C, dry, protected from light |
Supplier Comparison
| Supplier | Brand | Purity | Packaging |
|---|---|---|---|
| TRC (Canada) | TRC | 95% | 500mg, 2.5g |
| BIDU Chemicals (Hubei) | BIDU | 99% | 1kg, 5kg, 25kg |
| Shanghai Xinyu Bio | Millipore | N/A | Custom |
2. Key Applications
2-Bromo-4-cyanopyridine serves as a versatile building block in:
- Pharmaceuticals: Synthesis of kinase inhibitors, antiviral agents, and anticancer drugs.
- Agrochemicals: Intermediate for herbicides and fungicides.
- Material Science: Precursor for functionalized polymers and ligands.
3. Usage Guidelines
- Handle under inert gas (e.g., nitrogen) to prevent degradation.
- Use personal protective equipment (gloves, goggles) due to toxicity risks.
- Optimize reaction conditions (temperature: 80-120°C; solvents: DMF, THF).
4. Case Studies
Case 1: Antiviral Drug Intermediate
A leading pharmaceutical company used 2-bromo-4-cyanopyridine to synthesize a key intermediate for a protease inhibitor, achieving 92% yield via Suzuki-Miyaura coupling.
Case 2: Agrochemical Development
2-Bromo-4-cyanopyridine was functionalized to create a novel fungicide with broad-spectrum activity against Fusarium species.
5. Customer Success Stories
Customer A: Global CRO
Integrated 2-bromo-4-cyanopyridine into high-throughput screening for kinase targets, reducing lead optimization time by 30%.
Customer B: Specialty Chemical Manufacturer
Scaled up production of a boron-containing derivative (CAS: 75927-49-0) using 2-bromo-4-cyanopyridine, achieving ISO 9001 certification.
6. Contact for Quotations
For pricing, technical data sheets, or custom synthesis inquiries:
- Email: info@vivalr.com
- Phone: (86) 15866781826


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