3-(Trifluoromethyl)pyrid-2-ylhydrazine: Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Chemical Formula | C6H5F3N3 | C6H5F3N3 | C6H5F3N3 |
| Purity | ≥99.5% | 98.0-99.0% | 97.5-98.5% |
| Storage Temperature | 2-8°C | Ambient | 0-5°C |
Key Differentiators: Superior thermal stability (decomposition point 215°C vs market average 195°C), HPLC-verified purity, and nitrogen-sealed packaging.
2. Key Applications & Functional Properties
Pharmaceutical Intermediates
Enables synthesis of trifluoromethyl-containing kinase inhibitors with 40-60% improved reaction yields compared to traditional hydrazine derivatives.
Agrochemical Formulations
Critical component in next-generation fungicides, demonstrating 92% efficacy against Puccinia striiformis in field trials.
Material Science
Facilitates creation of thermally stable coordination polymers (Tg 185°C) for OLED applications.
3. Operational Guidelines & Best Practices
Handling Protocol
Always use anhydrous reaction conditions (H2O content <50ppm) to prevent hydrolysis. Recommended glovebox atmosphere: <0.1% O2.
Solvent Compatibility
Optimal performance in:
- DMSO (reaction time 2-3hr)
- THF (reaction time 4-5hr)
- Ethanol (limited to 60°C max)
4. Industry Application Case Studies
Case 1: Anticancer Drug Development
Used in 7-step synthesis of PD-1/PD-L1 inhibitor candidates, achieving 83% overall yield (Batch No. PH-2219).
Case 2: Crop Protection Agent
Enabled 35% cost reduction in prothioconazole analog production through streamlined coupling reactions.
5. Client Success Stories
ABC Pharmaceuticals (Shanghai)
“Achieved 99.2% purity in c-Met inhibitor API batches after switching to this product from previous suppliers.”
EuroChem Solutions GmbH
“Reduced catalyst loading by 60% in our fungicide production process while maintaining 98.5% conversion rates.”
6. Technical Consultation & Ordering
Request customized technical packages:
- COA: Certified purity documentation
- MSDS: Safety handling guidelines
- Custom synthesis protocols
Contact our technical team:
Email: info@vivalr.com
Tel: (86) 15866781826
Available in quantities from 100g to 200kg batches. GMP-grade production upon request.


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