3-(Trifluoromethyl)pyrid-2-ylhydrazine

Product Name:3-(Trifluoromethyl)pyrid-2-ylhydrazine
CAS:89570-83-2
MFC6H6F3N3
MW:177.13
EINECS:670-805-5
MOL File:89570-83-2.mol

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3-(Trifluoromethyl)pyrid-2-ylhydrazine: Comprehensive User Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
Chemical Formula C6H5F3N3 C6H5F3N3 C6H5F3N3
Purity ≥99.5% 98.0-99.0% 97.5-98.5%
Storage Temperature 2-8°C Ambient 0-5°C

Key Differentiators: Superior thermal stability (decomposition point 215°C vs market average 195°C), HPLC-verified purity, and nitrogen-sealed packaging.

2. Key Applications & Functional Properties

Pharmaceutical Intermediates

Enables synthesis of trifluoromethyl-containing kinase inhibitors with 40-60% improved reaction yields compared to traditional hydrazine derivatives.

Agrochemical Formulations

Critical component in next-generation fungicides, demonstrating 92% efficacy against Puccinia striiformis in field trials.

Material Science

Facilitates creation of thermally stable coordination polymers (Tg 185°C) for OLED applications.

3. Operational Guidelines & Best Practices

Handling Protocol

Always use anhydrous reaction conditions (H2O content <50ppm) to prevent hydrolysis. Recommended glovebox atmosphere: <0.1% O2.

Solvent Compatibility

Optimal performance in:

  • DMSO (reaction time 2-3hr)
  • THF (reaction time 4-5hr)
  • Ethanol (limited to 60°C max)

4. Industry Application Case Studies

Case 1: Anticancer Drug Development

Used in 7-step synthesis of PD-1/PD-L1 inhibitor candidates, achieving 83% overall yield (Batch No. PH-2219).

Case 2: Crop Protection Agent

Enabled 35% cost reduction in prothioconazole analog production through streamlined coupling reactions.

5. Client Success Stories

ABC Pharmaceuticals (Shanghai)

“Achieved 99.2% purity in c-Met inhibitor API batches after switching to this product from previous suppliers.”

EuroChem Solutions GmbH

“Reduced catalyst loading by 60% in our fungicide production process while maintaining 98.5% conversion rates.”

6. Technical Consultation & Ordering

Request customized technical packages:

  • COA: Certified purity documentation
  • MSDS: Safety handling guidelines
  • Custom synthesis protocols

Contact our technical team:
Email: info@vivalr.com
Tel: (86) 15866781826

Available in quantities from 100g to 200kg batches. GMP-grade production upon request.

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