6-(Chloromethyl)uracil Product Guide
Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Functional Advantages
- 3. Operational Guidelines & Best Practices
- 4. Industry Use Cases
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Specifications & Comparative Analysis
| Parameter | 6-(Chloromethyl)uracil | 5-(Chloromethyl)uracil | Unsubstituted Uracil |
|---|---|---|---|
| CAS Number | 53902-25-7 | N/A | 66-22-8 |
| Molecular Formula | C5H5ClN2O2 | C5H5ClN2O2 | C4H4N2O2 |
| Purity | >98% (HPLC) | 95-97% | 99% |
| Reactivity | High (Chloromethyl group) | Moderate | Low |
2. Key Applications & Functional Advantages
2.1 Pharmaceutical Intermediates
Enables precise molecular modifications in antiviral drug development (e.g., nucleoside analogs)
2.2 Polymer Modification
Facilitates covalent bonding in smart material synthesis through its reactive chloromethyl group
3. Operational Guidelines & Best Practices
3.1 Storage Recommendations
Store at 2-8°C under inert gas with desiccant
3.2 Reaction Optimization
Use polar aprotic solvents (DMF/DMSO) at 40-60°C for nucleophilic substitutions
4. Industry Use Cases
4.1 Anticancer Prodrug Synthesis
Modified uracil derivatives for targeted chemotherapy agents
4.2 DNA Probe Development
Fluorescent labeling applications in molecular diagnostics
5. Client Success Stories
5.1 Pharma Company A (2023)
Challenge: Needed stable intermediate for HCV protease inhibitor
Solution: Customized 6-(Chloromethyl)uracil synthesis
Result: 22% yield improvement vs traditional routes
5.2 Biotech Startup B (2024)
Challenge: Required modified nucleobases for mRNA vaccine research
Solution: Batch-specific purity optimization
Result: Achieved 99.2% purity for critical conjugation steps
6. Request Customized Solutions
Contact our technical team for:
– Bulk pricing
– Custom synthesis
– Regulatory support
Email: info@vivalr.com
Tel: (86) 15866781826


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