2,6-Dichloro-3-iodopyridine

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2,6-Dichloro-3-iodopyridine: Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 2,6-Dichloro-3-iodopyridine Similar Halopyridines
Chemical Formula C5H2Cl2IN Varies by substitution pattern
Molecular Weight 304.34 g/mol 250-350 g/mol range
CAS Number 343781-41-7 Dependent on structure
Purity Grade ≥98% (HPLC) Typically 95-99%
Storage Conditions 2-8°C in inert atmosphere Similar requirements

2. Industrial Applications & Functional Uses

Core Applications:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for novel pesticides
  • Ligands in catalytic systems
  • Building blocks for OLED materials
  • Cross-coupling reaction substrates

3. Application Methodologies

Typical Reaction Protocols:

  1. Suzuki-Miyaura Coupling:

    0.1 mmol substrate + 1.2 eq boronic acid in DME/H2O (3:1)
  2. Ullmann-Type Reactions:

    Catalyzed by CuI/1,10-phenanthroline at 110°C
  3. Sonogashira Coupling:

    Pd(PPh3)4/CuI system in Et3N

4. Case Studies

Case 1: Anticancer Drug Development

Used as key intermediate in Bruton’s tyrosine kinase (BTK) inhibitor synthesis, achieving 92% yield in Buchwald-Hartwig amination.

Case 2: Electronic Material Synthesis

Implemented in π-conjugated polymer synthesis for organic photovoltaics, enhancing charge transport properties by 40%.

5. Client Success Stories

Client A: European Pharma Innovator

  • Application: JAK2 inhibitor development
  • Result: Reduced synthesis steps from 5 to 3
  • Scale: 15kg pilot production

Client B: US Agrochemical Leader

  • Application: Novel insecticide active ingredient
  • Result: 68% efficacy improvement vs. previous generation
  • Scale: Multi-ton annual procurement

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (1kg+ quantities)
  • Custom halogenation patterns
  • GMP-grade manufacturing
  • Regulatory support documentation

Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • Strict QC: GC/MS, NMR, HPLC analysis
  • Global shipping capabilities
  • Technical consultation included
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