2-Amino-5-chloro-3-fluoropyridine

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2-Amino-5-chloro-3-fluoropyridine: Comprehensive User Guide

Table of Contents

1. Basic Information & Specifications

CAS Number: 374624-45-4

Molecular Formula: C5H4ClFN2

Molecular Weight: 146.55 g/mol

Key Parameters Comparison

Parameter Specification Industry Standard
Purity ≥98% (HPLC) ≥95%
Melting Point 89-92°C 85-95°C
Storage 2-8°C in inert gas Ambient (limited stability)

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Widely used in synthesis of kinase inhibitors (e.g., EGFR inhibitors) and anticancer agents due to its unique halogen-substituted pyridine structure.

Agrochemical Development

Critical component in next-generation fungicides and herbicides, particularly effective against Phytophthora infestans (potato blight pathogen).

Material Science

Building block for liquid crystal materials and OLED intermediates requiring precise electronic properties.

3. Industry Case Studies

Case Study 1: Oncology Drug Development

Client: Top 10 Global Pharma Company

Application: Synthesis of third-generation BTK inhibitor

Result: Achieved 92% yield in key coupling reaction, reduced purification steps from 5 to 2

Case Study 2: Agrochemical Innovation

Client: EU-based Crop Protection Leader

Application: Novel systemic fungicide formulation

Result: 40% improvement in rainfastness compared to conventional pyridine derivatives

4. Supplier Comparison

Supplier Purity Lead Time MOQ Price/kg
Supplier A 98% 4 weeks 100g $1,850
Supplier B 97% 2 weeks 1kg $1,650
Vivalr Chem 99% 1 week 50g $1,720

5. Request a Quote

Contact our technical team for:

  • Custom synthesis options
  • Bulk pricing (10kg+ orders)
  • Regulatory support (REACH, TSCA)

Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • GC/HPLC batch analysis reports
  • Global shipping with cold chain logistics
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