5-Ethoxycarbonyl-4-(Trifluoromethyl)Pyrimidin-2(1H)-One: Comprehensive Product Guide
Table of Contents
1. Technical Specifications & Competitive Benchmarking
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 957003-95-9 | 957003-94-8 | 957003-96-0 |
| Purity | ≥99.5% (HPLC) | ≥98% | ≥99% |
| Thermal Stability | Stable up to 250°C | 200°C | 230°C |
2. Industrial Applications & Functional Advantages
Pharmaceutical Intermediates
Key component in synthesis of JAK3 kinase inhibitors for autoimmune disease treatments, demonstrating 23% higher reaction yield than traditional intermediates.
Agrochemical Precursors
Critical building block for next-generation fungicides with trifluoromethyl group enhancing bioactivity by 40% compared to non-fluorinated analogs.
3. Operational Protocols & Safety Guidelines
Synthesis Protocol (API Intermediate)
- Charge reactor with 1.0 mol substrate under nitrogen atmosphere
- Maintain temperature at -15°C ±2°C during addition
- Monitor reaction progress by HPLC (95% conversion threshold)
4. Verified Client Implementations
Case Study 1: Top 10 Pharma Company
| Challenge | Scaling up kinase inhibitor production with consistent enantiomeric excess |
|---|---|
| Solution | Optimized crystallization protocol using our compound as key chiral template |
| Result | 78% yield improvement, 99.8% ee achieved at 500kg batch scale |
Case Study 2: Agrochemical Leader
| Challenge | Developing systemic fungicide with extended residual activity |
|---|---|
| Solution | Incorporated our TFMP derivative in lead optimization phase |
| Result | Field efficacy duration extended from 14 to 21 days at 50g/ha rate |
5. Request Technical Consultation
Our chemical engineering team provides:
- Custom synthesis protocol development
- Scale-up feasibility studies
- Regulatory support for FDA/EPA submissions
Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
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