1. Product Overview & Specifications
Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate (CAS: 778-97-2) is a specialized pyrimidine derivative with the molecular formula C9H13N3O2S and a molecular weight of 227.28 g/mol. This compound features a pyrimidine ring substituted with amino, ethylthio, and ethyl carboxylate functional groups, making it a versatile intermediate in organic synthesis.
Key Specifications:
Parameter | Value |
---|---|
CAS Number | 778-97-2 |
Molecular Formula | C9H13N3O2S |
Molecular Weight | 227.28 g/mol |
Synonyms | 4-Amino-2-(ethylthio)-5-pyrimidinecarboxylic acid ethyl ester; 2-Ethylthio-4-aminopyrimidine-5-carboxylate |
Comparative Analysis:
Compound | Substituent | Molecular Weight | Key Applications |
---|---|---|---|
Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate | Ethylthio | 227.28 | Pharmaceutical intermediates |
Ethyl 4-amino-2-(methylthio)-5-pyrimidinecarboxylate | Methylthio | 213.25 | Agrochemical synthesis |
2. Key Applications
This compound is primarily utilized as a high-value intermediate in the following domains:
- Pharmaceuticals: Serves as a precursor in the synthesis of antiviral and anticancer agents due to its reactive pyrimidine core.
- Agrochemicals: Used to develop herbicides and fungicides with enhanced selectivity.
- Chemical Research: Acts as a building block for novel heterocyclic compounds in medicinal chemistry.
3. Usage Guidelines
- Storage: Store in a cool, dry environment (2-8°C) under inert gas to prevent degradation.
- Handling: Use PPE (gloves, goggles) to avoid direct contact; ensure adequate ventilation.
- Solubility: Soluble in DMSO, DMF, and methanol; insoluble in water.
4. Industry Use Cases
- Drug Development: Integrated into kinase inhibitor synthesis for targeted cancer therapies.
- Material Science: Facilitates the creation of photoactive compounds for organic electronics.
5. Client Success Stories
Note: Specific client details are confidential. Below are generalized examples:
- Case 1: A European pharmaceutical company utilized this compound to optimize the synthesis route of a Phase III antiviral drug, reducing production costs by 18%.
- Case 2: A Asian agrochemical manufacturer incorporated it into a next-generation fungicide formulation, achieving 95% efficacy against resistant pathogens.
6. Contact for Custom Solutions
For technical inquiries or bulk orders, contact our team:
- Email: info@vivalr.com
- Phone: (86) 15866781826