3,6-Dibromopyridazide: Comprehensive Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | 3,6-Dibromopyridazide | Comparable Compounds |
|---|---|---|
| CAS Number | 17973-86-3 | N/A |
| Molecular Formula | C4H2Br2N2 | C5H3BrN2 |
| Molecular Weight | 237.88 g/mol | 185.98 g/mol |
| Density | 2.2±0.1 g/cm3 | 1.8±0.1 g/cm3 |
| Melting Point | 116-117°C | 98-100°C |
| Boiling Point | 327.5±22.0°C | 280±15°C |
| Flash Point | 151.9±22.3°C | 130±10°C |
2. Key Applications
This heterocyclic compound serves as:
- Pharmaceutical Intermediate: Critical precursor in kinase inhibitor synthesis
- Biochemical Research: Functional group donor in nucleotide modification
- Material Science: Cross-linking agent for specialty polymers
- Agrochemical Development: Building block for crop protection agents
3. Usage Guidelines
Handling Protocols
- Storage: Maintain at 2-8°C in sealed amber glass containers
- Ventilation: Use fume hood for all handling procedures
- PPE Requirements: Neoprene gloves, chemical goggles, and Type B lab coats
Reaction Optimization
- Optimal coupling temperature: 40-50°C
- Recommended solvent system: DCM/THF (3:1 ratio)
- Catalyst efficiency: 0.5 mol% Pd(PPh3)4
4. Industry Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: Key intermediate in third-generation BTK inhibitor synthesis
Outcome: 23% yield improvement vs. previous synthetic route
Case 2: Advanced Polymer Research
Client: Specialty Materials Manufacturer (NASDAQ-listed)
Application: Cross-linking agent for high-temperature resins
Result: Achieved 315°C thermal stability (15% improvement)
5. Contact Information
For technical specifications or bulk inquiries:
Email: info@vivalr.com
Tel: (86) 15866781826
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